Validation of synthesized normal-resolution image data generated from high-resolution acquisitions on a commercial CT scanner

Medical Physics
Andrew M HernandezJohn M Boone

Abstract

To validate a normal-resolution (NR) simulation (NRsim) algorithm that uses high-resolution (HR) or super-high resolution (SHR) acquisitions on a commercial HR computed tomography (CT) scanner by comparing image quality between NRsim-generated images and actual NR images. NRsim is intended to allow direct comparison between normal-resolution CT and HR/SHR reconstructions in clinical investigations, without repeating exams. The Aquilion Precision CT (Canon Medical Systems Corporation) HR CT scanner has three resolution modes resulting from detector binning in the channel (x-y) and row (z) directions. For NR, each detector element is 0.5 mm × 0.5 mm along the channel and row directions, 0.25 mm × 0.5 mm for HR, and 0.25 mm × 0.25 mm for SHR. The NRsim algorithm simulates NR acquisitions from HR or SHR acquisitions (termed NRHR and NRSHR , respectively) by downsampling the pre-log raw data in the channel direction for the HR acquisitions and in the channel and row direction for the SHR acquisition. The downsampled data are then reconstructed using the same process as NR. The axial modulation transfer function (MTF), slice sensitivity profile (SSP), and CT number accuracy were measured using the Catphan 600 phantom, and the three-d...Continue Reading

References

Oct 1, 1985·Journal of the Optical Society of America. A, Optics and Image Science·K J MyersG W Seeley
Apr 1, 1994·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·A E Burgess
Dec 5, 2002·Medical Physics·J H SiewerdsenD A Jaffray
Feb 25, 2009·Medical Physics·Parinaz MassoumzadehBruce R Whiting
Oct 1, 2009·European Radiology·R M S JoemaiW J H Veldkamp
Sep 24, 2011·Journal of the American College of Cardiology·James A GoldsteinUNKNOWN CT-STAT Investigators
Mar 8, 2013·Medical Physics·Joshua M WilsonEhsan Samei
Jul 2, 2015·Medical Physics·Bruce R WhitingJeffrey F Williamson
Jun 24, 2017·IEEE Transactions on Medical Imaging·Lucas R BorgesMarcelo A C Vieira
Jun 11, 2019·AJR. American Journal of Roentgenology·Francesco RiaEhsan Samei
Feb 11, 2020·European Radiology·Luuk J OostveenIoannis Sechopoulos

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Citations

Feb 21, 2021·Medical Physics·Andrew M HernandezJohn M Boone

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