Validation of the Baveno VI and the expanded Baveno VI criteria to identify patients who could avoid screening endoscopy

Liver International : Official Journal of the International Association for the Study of the Liver
Joohwan BaeSeung Woon Paik

Abstract

The Baveno VI and the expanded Baveno VI criteria were proposed to help identify patients who could safely avoid screening endoscopies for clinically significant varices among patients with compensated advanced chronic liver disease. However, these criteria require cross-validation, especially in Asian populations where the aetiologies of liver disease are different. A total of 1035 patients, including 282 patients with compensated advanced chronic liver disease of different aetiology, were analysed. The compensated advanced chronic liver disease was defined by liver stiffness measurement ≥10 kPa, Child-Pugh class A and absence of prior liver decompensation. High-risk varix was defined as a grade ≥2 oesophageal varix, any varix with a red colour sign or gastric varices. High-risk varixs were present in 19.5% (55/282 patients) with compensated advanced chronic liver disease. Among compensated advanced chronic liver disease patients, the expanded criteria could spare more endoscopies (51.7%) than the original criteria (27.6%). However, the expanded criteria missed a greater number of high-risk varixs (6.8%) than the original criteria (3.8%). When stratified according to liver disease aetiology, the negative predictive values for ...Continue Reading

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Citations

Aug 22, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Paul CalèsDavide Festi
Dec 28, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Han Ah LeeSoon Ho Um
Jan 10, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·María I GaeteCarlos Benítez
Jun 9, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Matteo GarcovichMaurizio Pompili
Aug 25, 2019·Liver International : Official Journal of the International Association for the Study of the Liver·Horia StefanescuDavide Festi
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Dec 6, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Bingqiong WangHong You
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Aug 25, 2021·Scandinavian Journal of Gastroenterology·Joel Ferreira-SilvaGuilherme Macedo

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