Validation of the Dyspnea Exertion Scale of Breathlessness in People With Life-Limiting Illness

Journal of Pain and Symptom Management
Jacob SandbergMagnus Ekström

Abstract

Although chronic breathlessness is common in life-limiting illnesses, validated feasible instruments to measure functional impact of the symptom in this population are scarce. We aimed to validate the Dyspnea Exertion Scale (DES) compared with the modified Medical Research Council (mMRC) breathlessness scale for test-retest reliability, concurrent validity, and responsiveness in people with life-limiting illness. A total of 188 participants, 66% males, with chronic breathlessness, mostly (70%) because of chronic pulmonary disease (chronic obstructive pulmonary disease) self-reported evening scores of mMRC, DES, Numerical Rating Scale (NRS), and Eastern Cooperative Oncology Group during nine days. About 44% (n = 81) scored the highest score on mMRC indicating a ceiling effect not seen with DES. Both scales had moderate-to-good test-retest agreement (89% DES; 84% mMRC; P < 0.001 for both). Analyses for concurrent validity showed that higher DES and mMRC scores were correlated with higher NRS breathlessness intensity scores and Eastern Cooperative Oncology Group scores throughout the nine days. In longitudinal analyses, DES (r = 0.30; P < 0.001) was more responsive to change in NRS score during nine days than the mMRC (r = 0.16; P...Continue Reading

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Citations

Oct 31, 2019·Thorax·Daisy J A Janssen, Miriam J Johnson
Jun 12, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Hayley LewthwaiteMagnus Ekström
Jul 19, 2021·Journal of Physiotherapy·Mariana Hoffman, Anne E Holland

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