Validation of the efficacy of the prognostic factor score in the Japanese severity criteria for severe acute pancreatitis: A large multicenter study

United European Gastroenterology Journal
Tsukasa IkeuraToshihiko Mayumi

Abstract

The Japanese severity criteria for acute pancreatitis (AP), which consist of a prognostic factor score and contrast-enhanced computed tomography grade, have been widely used in Japan. This large multicenter retrospective study was conducted to validate the predictive value of the prognostic factor score for mortality and complications in severe AP patients in comparison to the Acute Physiology and Chronic Health Evaluation II (APACHE II) score. Data of 1159 patients diagnosed with severe AP according to the Japanese severity criteria for AP were retrospectively collected in 44 institutions. The area under the curve (AUC) for the receiver-operating characteristic curve of the prognostic factor score for predicting mortality was 0.78 (95% confidence interval (CI), 0.74-0.82), whereas the AUC for the APACHE II score was 0.80 (95% CI, 0.76-0.83), respectively. There were no significant differences in the AUC for predicting mortality between two scoring systems. The AUCs of the prognostic factor scores for predicting the need for mechanical ventilation, the development of pancreatic infection, and severe AP according to the revised Atlanta classification were 0.84 (95% CI, 0.81-0.86), 0.73 (95% CI, 0.69-0.77), and 0.83 (95% CI, 0.81...Continue Reading

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Citations

Jun 12, 2019·International Journal of Molecular Sciences·Pedro Silva-VazJosé Guilherme Tralhão
Mar 12, 2020·Annals of the Royal College of Surgeons of England·C A GomesF Catena
Aug 21, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kazuhiro MinamiTakanori Kanai
Apr 29, 2021·Arquivos De Gastroenterologia·José Roberto AlvesMarcelo Bianchini Teive
May 5, 2021·Expert Review of Gastroenterology & Hepatology·Yuki Ong, Vishal G Shelat
Oct 5, 2021·Journal of Basic and Clinical Physiology and Pharmacology·Tosan Peter OmayoneSamuel Oluwaseun Dinakin

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