PMID: 9179103Apr 1, 1997Paper

Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement

Journal of Clinical Epidemiology
M GroenvoldN K Aaronson

Abstract

Patient-rated questionnaires are increasingly used to assess health-related quality of life. We studied one aspect of the validity of such measures that has rarely been investigated do patients interpret questionnaires in the same way as do the researchers reporting the results? If not, there may be a problem. We employed the EORTC QLQ-C30 quality-of-life questionnaire to study 95 cancer patients and measured the agreement between (1) the patient's self-assessment and (2) an observer's rating of the patient's open-ended responses to the same questionnaire administered as an interview. The observer made qualitative recordings describing potential misinterpretations. The agreement between patients' and observers' ratings was high (median kappa = 0.85, range 0.49-1.00). The qualitative data revealed a few minor validity problems. One of these, selective reporting, may lead to systematic errors; some patients reported only what they considered "relevant" symptoms. The combination of quantitative and qualitative methods proved useful for questionnaire validation.

References

Jan 1, 1990·Journal of Clinical Epidemiology·D V Cicchetti, A R Feinstein
Jan 1, 1990·Journal of Clinical Epidemiology·A R Feinstein, D V Cicchetti
Feb 1, 1989·The British Journal of Surgery·E J RutgersH M Kluck
Jan 1, 1987·Journal of Chronic Diseases·G H GuyattJ L Keller
Jun 1, 1995·Journal of Clinical Epidemiology·M GroenvoldS Kreiner
Oct 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·H E Niezgoda, J L Pater
Jun 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·V SigurdardóttirM Sullivan
Apr 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·G I Ringdal, K Ringdal

❮ Previous
Next ❯

Citations

Aug 13, 2005·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lis AdamsenMikael Rorth
Aug 2, 2005·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Christopher G LisDigant Gupta
Jun 24, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jeff A SloanUNKNOWN Clinical Significance Consensus Meeting Group
Nov 23, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Digant GuptaJames F Grutsch
Jan 24, 2007·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Digant GuptaJames F Grutsch
Aug 9, 2007·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Christopher G LisJames F Grutsch
Apr 4, 2008·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Christopher G LisJames F Grutsch
May 21, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lone RossMogens Groenvold
Jun 29, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Donald P BraunEdgar D Staren
Aug 19, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Zheng YangChonghua Wan
Apr 26, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lone RossMogens Groenvold
Jun 12, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Chris L PashosZeba M Khan
Oct 14, 2006·Breast Cancer Research and Treatment·Mogens GroenvoldHenning T Mouridsen
Jun 7, 2012·Journal of Clinical Psychology in Medical Settings·Angélique Bonnaud-AntignacVéronique Sebille
Apr 25, 2013·Journal of Clinical Psychology in Medical Settings·M Angeles Pérez-San-GregorioM Esther Rincón-Fernández
Jun 28, 2008·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Torquil WattUlla Feldt-Rasmussen
Feb 13, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Michelle PloughmanMarshall Godwin
May 25, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Wei-Chu ChieYung-Chie Lee
Dec 6, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kirstine M RobinsonAllan Krasnik
May 10, 2012·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Shozo Ohsumi, Kojiro Shimozuma
Nov 5, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Pernille Tine JensenMogens Groenvold
Jul 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A M Cull
Jun 5, 2003·Breast Cancer Research and Treatment·Jutta EngelDieter Hölzel
Oct 9, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Helga GimbelAnn Tabor
Oct 17, 2006·Journal of Palliative Medicine·Anil GaryaliEduardo Bruera
Jul 26, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C WanC Zhang
May 25, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A Schlesinger-RaabJ Engel
Sep 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D E EdiebahUNKNOWN Quality of Life Department and Patient Reported Outcome and Behavioural Evidence (PROBE)
Jul 31, 2008·Journal of the National Cancer Institute·Christine HerbstUNKNOWN Cochrane Haematological Malignancies Group
Sep 1, 2007·American Journal of Clinical Oncology·Angelo Bezerra de Souza FêdeAuro Del Giglio
Mar 9, 2012·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Allison M QuickDouglas Martin
Oct 11, 2012·Cancer Nursing·Canhua XiaoDeborah Watkins Bruner
Nov 17, 2012·Respiration; International Review of Thoracic Diseases·Natasha F SaburAlain Tremblay
Jul 11, 2013·BMC Urology·Digant GuptaEdgar D Staren
Mar 21, 2013·Journal of Ovarian Research·Digant GuptaMaurie Markman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.