Validation of the LET classification

Phlebology
R H W StrijkersC H A Wittens

Abstract

Acute thrombus removal therapies may reduce post-thrombotic syndrome in certain deep venous thrombosis patients. The LET classification is designed to identify patients at high risk for developing post-thrombotic syndrome in the acute phase using thrombus location and extent. This study evaluates the use of the LET classification to predict post-thrombotic syndrome in a cohort of patients after deep venous thrombosis. A cohort of 660 deep venous thrombosis patients was invited to participate and fill out a questionnaire with Quality of life questionnaires, basic information, a modified self-assessment version of the Villalta scale for post-thrombotic syndrome and potential confounders. Original data on thrombus extension was available, and the LET classes were determined. Obtained information was analysed using ANOVA and in a multiple logistic regression model to correct for confounders. All different LET classes were compared to post-thrombotic syndrome occurrence, post-thrombotic syndrome prediction and disease specific quality of life scores (VEINES-Sym/Qol). Three hundred and fifteen patients responded, and in 309 a post-thrombotic syndrome score was distilled. LET I,II,III (n = 63) had an odds ratio of 3.4(1.2-9.2) for pre...Continue Reading

References

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Citations

Feb 20, 2016·British Medical Bulletin·Prakash SahaAlberto Smith
Apr 12, 2016·Journal of Thrombosis and Haemostasis : JTH·R L M KurstjensC H A Wittens
Sep 18, 2016·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Ralph L M KurstjensCees H A Wittens
Feb 27, 2016·Phlebology·Patrick Navin, Gerard J O'Sullivan
Oct 20, 2017·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Mayank RoyTerry King
Nov 5, 2016·The Cochrane Database of Systematic Reviews·Lindsay RobertsonAnne Burdess
Aug 21, 2020·Phlebology·Doireann Patricia JoyceTjun Yip Tang
Jun 18, 2020·Research and Practice in Thrombosis and Haemostasis·Pascale NottenArina J Ten Cate-Hoek
Sep 28, 2017·Case Reports in Vascular Medicine·Ata FirooziParham Sadeghipour
Dec 15, 2020·Research and Practice in Thrombosis and Haemostasis·Jean-Philippe GalanaudJean-Luc Bosson
Apr 25, 2021·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Soroosh ShekarchianHouman Jalaie
May 26, 2021·Journal of the American Heart Association·Pascale NottenArina J Ten Cate-Hoek

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Software Mentioned

Qol
SPSS
VEINES
Sym

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