Abstract
Acute thrombus removal therapies may reduce post-thrombotic syndrome in certain deep venous thrombosis patients. The LET classification is designed to identify patients at high risk for developing post-thrombotic syndrome in the acute phase using thrombus location and extent. This study evaluates the use of the LET classification to predict post-thrombotic syndrome in a cohort of patients after deep venous thrombosis. A cohort of 660 deep venous thrombosis patients was invited to participate and fill out a questionnaire with Quality of life questionnaires, basic information, a modified self-assessment version of the Villalta scale for post-thrombotic syndrome and potential confounders. Original data on thrombus extension was available, and the LET classes were determined. Obtained information was analysed using ANOVA and in a multiple logistic regression model to correct for confounders. All different LET classes were compared to post-thrombotic syndrome occurrence, post-thrombotic syndrome prediction and disease specific quality of life scores (VEINES-Sym/Qol). Three hundred and fifteen patients responded, and in 309 a post-thrombotic syndrome score was distilled. LET I,II,III (n = 63) had an odds ratio of 3.4(1.2-9.2) for pre...Continue Reading
References
May 10, 2008·Journal of Thrombosis and Haemostasis : JTH·S R KahnJ S Ginsberg
Jun 3, 2008·Journal of Vascular Surgery·Nicos LabropoulosPeter J Pappas
Nov 20, 2008·Annals of Internal Medicine·Susan R KahnJeffrey S Ginsberg
Dec 17, 2011·Lancet·Tone EndenUNKNOWN CaVenT Study Group
Jan 27, 2012·Journal of Vascular Surgery·Anthony J ComerotaZakaria Assi
Feb 15, 2012·Phlebology·M A F de WolfS R Kahn
Feb 15, 2012·Phlebology·C W K P Arnoldussen, C H A Wittens
Jan 3, 2013·Journal of Thrombosis and Haemostasis : JTH·J P GalanaudS R Kahn
Apr 6, 2013·Phlebology·S K van der VeldenA Sommer
Dec 10, 2013·Lancet·Susan R KahnUNKNOWN SOX trial investigators
Aug 22, 2014·Current Opinion in Cardiology·Jean-Philippe Galanaud, Susan R Kahn
Citations
Feb 20, 2016·British Medical Bulletin·Prakash SahaAlberto Smith
Apr 12, 2016·Journal of Thrombosis and Haemostasis : JTH·R L M KurstjensC H A Wittens
Sep 18, 2016·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Ralph L M KurstjensCees H A Wittens
Jun 3, 2016·Phlebology·Rob Hw StrijkersCees Ha Wittens
Feb 27, 2016·Phlebology·Patrick Navin, Gerard J O'Sullivan
Oct 20, 2017·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Mayank RoyTerry King
Nov 5, 2016·The Cochrane Database of Systematic Reviews·Lindsay RobertsonAnne Burdess
Jul 28, 2018·Phlebology·Guang LiuXinwu Lu
Nov 2, 2019·Vascular·Jun ZhuWen-Hui Li
Jul 1, 2020·Thrombosis and Haemostasis·Pascale NottenArina J Ten Cate-Hoek
Aug 21, 2020·Phlebology·Doireann Patricia JoyceTjun Yip Tang
Jun 18, 2020·Research and Practice in Thrombosis and Haemostasis·Pascale NottenArina J Ten Cate-Hoek
Sep 28, 2017·Case Reports in Vascular Medicine·Ata FirooziParham Sadeghipour
Aug 6, 2020·Diagnostics·Romaric LoffroyOlivier Chevallier
Dec 15, 2020·Research and Practice in Thrombosis and Haemostasis·Jean-Philippe GalanaudJean-Luc Bosson
Apr 25, 2021·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Soroosh ShekarchianHouman Jalaie
May 26, 2021·Journal of the American Heart Association·Pascale NottenArina J Ten Cate-Hoek