Validation of the LupusPRO version 1.8: an update to a disease-specific patient-reported outcome tool for systemic lupus erythematosus

Lupus
D R AzizoddinM Jolly

Abstract

Objectives LupusPRO has shown good measurement properties as a disease-specific patient-reported outcome tool in systemic lupus erythematosus (SLE). For the purpose of clinical trials, the version 1.7 (v1.7) domain of Pain-Vitality was separated into distinct Pain, Vitality and Sleep domains in v1.8, and the psychometric properties examined. Methods A total of 131 consecutive SLE patients were self-administered surveys assessing fatigue (FACIT, SF-36), pain (Pain Inventory, SF-36), insomnia (Insomnia Severity Index), emotional health (PHQ-9, SF-36) and quality of life (SF-36, LupusPRO) at routine care visits. Internal consistency reliability (ICR) for each domain was obtained using Cronbach's alpha. The convergent construct validity of LupusPRO domains with corresponding SF-36 domains or tools were tested using Spearman correlation. Varimax rotations were conducted to assess factor structures of the LupusPRO v1.8. Results Mean (SD) age was 40.04 (14.10) years. Scores from the LupusPRO-Sleep domain strongly correlated with insomnia scores, while LupusPRO-Vitality correlated strongly with fatigue (FACIT) and SF-36 vitality. The LupusPRO-Pain domain correlated strongly with pain (SF36 Bodily-Pain, Pain Inventory) scores. Similarly...Continue Reading

References

Nov 1, 1982·Arthritis and Rheumatism·E M TanR J Winchester
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Sep 5, 2003·Journal of Clinical Epidemiology·Robert G MarxRussell F Warren
Aug 29, 2009·Arthritis and Rheumatism·Richard A FurieWilliam W Freimuth
Apr 7, 2012·Seminars in Arthritis and Rheumatism·Meenakshi JollyDaniel J Wallace
Jan 1, 2013·Psychosomatics·David E KarolMegan E B Clowse
Aug 13, 2013·Clinical Rheumatology·Arif KayaMeenakshi Jolly
Aug 27, 2014·Arthritis Care & Research·Chi Chiu MokMeenakshi Jolly
May 20, 2015·Health and Quality of Life Outcomes·Sarah AcasterLee F Allen

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Citations

Feb 15, 2019·The Journal of Animal Ecology·Ana T MarquesJoão P Silva
Mar 26, 2019·Journal of the American Geriatrics Society·Krista L HarrisonKristine Yaffe
Sep 30, 2018·Expert Review of Clinical Immunology·Claudia Elera-FitzcarraldManuel F Ugarte-Gil
Jul 4, 2021·Rheumatic Diseases Clinics of North America·Narender Annapureddy, Meenakshi Jolly
Aug 28, 2021·Journal of Clinical Medicine·Matthew H NguyenSean G O'Neill

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Software Mentioned

SELENA
LupusPRO

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