Validation of the multimodal assessment of capacities in severe dementia: a novel cognitive and functional scale for use in severe dementia

Journal of Neurology
Sloane HellerPablo Martinez-Martin

Abstract

The multimodal assessment of capacities in severe dementia (MAC-SD), a novel cognitive and functional assessment, was developed for use with patients with severe dementia. Its psychometric attributes were examined in a unicenter, open, observational study. The MAC-SD along with the Spanish language Severe Mini Mental Exam were administered to 103 patients with a diagnosis of severe dementia. Psychometric analyses were performed to determine acceptability, reliability, validity, and responsiveness. As a whole, the MAC-SD sections showed no floor effects, satisfactory internal consistency, reproducibility, construct validity, precision, and sensitivity to change. The MAC-SD performed as a useful, valid, and potentially responsive tool to measure cognition and functioning in the most advanced stages of dementia.

References

Jun 1, 1990·Fortschritte der Neurologie-Psychiatrie·T BenkeF Gerstenbrand
Jul 1, 1996·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·G R FordL E Harrell
Nov 14, 1997·Age and Ageing·K JuvaR Tilvis
Jan 1, 1997·International Psychogeriatrics·S Auer, B Reisberg
Feb 2, 2002·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·H BeckermanA L Verbeek
Nov 29, 2002·Journal of Neural Transmission. Supplementum·F A SchmittA Stöffler
Jun 30, 2004·CNS Drugs·Thierry VoisinBruno Vellas
Dec 13, 2006·Journal of Clinical Epidemiology·Caroline B TerweeHenrica C W de Vet
May 8, 2007·International Psychogeriatrics·Barry Reisberg
Dec 19, 2008·Journal of Neurology, Neurosurgery, and Psychiatry·S A M SikkesB M J Uitdehaag
Aug 10, 2010·Journal of Alzheimer's Disease : JAD·Pablo Martínez-MartínUNKNOWN AD Research Unit Investigators
Oct 12, 2011·Journal of Alzheimer's Disease : JAD·Javier OlazaránPablo Martínez-Martín
Mar 21, 2012·Archives of Neurology·Charles BernickPaul Aisen
Apr 25, 2012·Journal of Neurology·Pablo Martinez-MartinAngel Ayuga-Martinez
Aug 30, 2012·American Journal of Alzheimer's Disease and Other Dementias·Yi XingJianping Jia
Nov 14, 2012·International Psychogeriatrics·Louise HallAimee Spector
Dec 29, 2012·Health and Quality of Life Outcomes·Hendramoorthy MaheswaranSarah Stewart-Brown

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.