Validation of the Saint George's Respiratory Questionnaire in Uganda

BMJ Open Respiratory Research
Brooks W MorganWilliam Checkley

Abstract

Chronic obstructive pulmonary disease (COPD) will soon be the third leading global cause of death and is increasing rapidly in low/middle-income countries. There is a need for local validation of the Saint George's Respiratory Questionnaire (SGRQ), which can be used to identify those experiencing lifestyle impairment due to their breathing. The SGRQ was professionally translated into Luganda and reviewed by our field staff and a local pulmonologist. Participants included a COPD-confirmed clinic sample and COPD-positive and negative members of the community who were enrolled in the Lung Function in Nakaseke and Kampala (LiNK) Study. SGRQs were assembled from all participants, while demographic and spirometry data were additionally collected from LiNK participants. In total, 103 questionnaires were included in analysis: 49 with COPD from clinic, 34 community COPD-negative and 20 community COPD-positive. SGRQ score varied by group: 53.5 for clinic, 34.4 for community COPD-positive and 4.1 for community COPD-negative (p<0.001). The cross-validated c statistic for SGRQ total score predicting COPD was 0.87 (95% CI 0.75 to 1.00). SGRQ total score was associated with COPD severity (forced expiratory volume in 1 s per cent of predicted)...Continue Reading

References

Jun 1, 1992·The American Review of Respiratory Disease·P W JonesP Littlejohns
Aug 1, 1997·American Journal of Respiratory and Critical Care Medicine·C B WilsonR Wilson
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·J L HankinsonK B Fedan
Feb 5, 2005·Respirology : Official Journal of the Asian Pacific Society of Respirology·UNKNOWN Asia Pacific COPD Roundtable Group
Aug 2, 2005·The European Respiratory Journal·M R MillerUNKNOWN ATS/ERS Task Force
Sep 25, 2008·Respirology : Official Journal of the Asian Pacific Society of Respirology·Shouchun PengXianming Hou
Jan 24, 2009·The European Respiratory Journal·M WeatherallR Beasley
Mar 13, 2010·The European Respiratory Journal·J BousquetL Zhi
Aug 5, 2010·Perceptual and Motor Skills·Theodoros A KatsoulasGeorge Baltopoulos
Jun 20, 2014·COPD·Davies AdeloyeHarry Campbell
Sep 7, 2014·The Lancet. Respiratory Medicine·Stephen B GordonWilliam J Martin
Jan 13, 2016·Journal of Global Health·Davies AdeloyeUNKNOWN Global Health Epidemiology Reference Group (GHERG)
Jan 28, 2016·Current Opinion in Pulmonary Medicine·Nour A AssadAkshay Sood
Sep 2, 2015·Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation·Chundak T SherpaWilliam Checkley

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