Validation of topographic hybrid single-photon emission computerized tomography with computerized tomography scan in patients with and without nonspecific chronic low back pain. A prospective comparative study

The Spine Journal : Official Journal of the North American Spine Society
Erik Van de KelftJohan Van Goethem

Abstract

The evidence for the treatment for nonspecific chronic low back pain (ns CLBP) is very weak. Besides the complexity of the pain experience, a good biological marker or tool enabling identification of a pain generator is lacking. Hybrid imaging, combining single-photon emission computerized tomography (SPECT) with computerized tomography (CT) scan, has been proposed as useful in the diagnostic workup of patients with CLBP. To evaluate the sensitivity of SPECT-CT in patients with ns CLBP (Group I) as compared with patients without CLBP (Group II). A prospective comparative study. Two hundred patients were enrolled: 96 in Group I and 104 in Group II. Only the physiological measurement of the incidence of hot spots was performed. The hot spots were rated as follows: 0=normal; 1=slightly colored (no hot spot on whole-body bone scan); and 2=clear hot spot (can be identified on the whole-body bone scan and confirmed on SPECT). To analyze the interobserver agreement when using this scoring system, a second independent reading was performed for 50 randomly chosen records. Two hundred patients divided into two groups were referred to the department of Medical and Molecular Imaging for a topographic SPECT-CT. The first group consisted of ...Continue Reading

References

Jul 14, 1994·The New England Journal of Medicine·M C JensenJ S Ross
Aug 14, 2003·The Orthopedic Clinics of North America·Helena Brisby
Mar 16, 2005·Lancet·Paul A Dieppe, L Stefan Lohmander
Mar 7, 2006·The Spine Journal : Official Journal of the North American Spine Society·Daniel S MulconreyPatrick A Harty
Mar 22, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·O AiraksinenUNKNOWN COST B13 Working Group on Guidelines for Chronic Low Back Pain
Oct 3, 2007·Annals of Internal Medicine·Roger ChouUNKNOWN American Pain Society Low Back Pain Guidelines Panel
Mar 27, 2009·Nuklearmedizin. Nuclear Medicine·Hanne AlbertPoul Flemming Høilund-Carlsen
Aug 1, 2009·The Spine Journal : Official Journal of the North American Spine Society·Daoud MakkiTagreed Toma
Dec 5, 2009·Seminars in Nuclear Medicine·Hans Van der WallSiri Kannangara
Jan 21, 2011·Chiropractic & Manual Therapies·Michael H CarstensenTarik-Zine Belhocine
Oct 25, 2012·Biochemia Medica·Mary L McHugh
Feb 16, 2013·International Orthopaedics·Hosam E MatarAnn-Marie Quigley
Apr 22, 2015·BMC Musculoskeletal Disorders·Jyri JärvinenEeva Rinne
Jul 15, 2015·Indian Journal of Nuclear Medicine : IJNM : the Official Journal of the Society of Nuclear Medicine, India·Natalie ShurGopinath Gnanasegaran
Jul 16, 2015·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·David FreiermuthWilhelm Ruppen
Mar 8, 2016·Diagnostic and Interventional Imaging·M MoustarhfirB Dallaudière
Jun 28, 2016·Disease-a-month : DM·Joseph AllevaAndrea Kristin Origenes
Aug 3, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Katariina LuomaEeva Rinne

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