Validation study of a central venous pressure-based protocol for the management of neurosurgical patients with hyponatremia and natriuresis

Neurosurgery
S C DamarajuM J Chandy

Abstract

We had previously suggested a protocol for the management of neurosurgical patients with hyponatremia and natriuresis that was based on their volume status as determined by actual blood volume measurements. All patients in that study were found to be hypovolemic or normovolemic and responded, within 72 hours, to salt and fluid replacement. In the present study, the validity of that protocol was tested using central venous pressure as the sole measure of volume status of patients with hyponatremia and natriuresis. Twenty-five consecutive patients (26 cases) who fulfilled the inclusion criteria typically used to diagnose the syndrome of inappropriate secretion of antidiuretic hormone were included in the study. Central venous pressure was used to classify patients as hypovolemic (< 5 cm of water), normovolemic (6-10 cm of water), or hypervolemic (> 11 cm of water). Hypovolemic patients were given fluids (50 ml/kg/d) and salt (12 g/d). Normovolemic patients were given normal fluid with 12 g of salt per day. In addition, patients with anemia (hematocrit, < 27%) were administered whole blood. The end point was a serum sodium of more than or equal to 130 mEq/L measured in two consecutive samples 12 hours apart or 72 hours after entry...Continue Reading

Citations

Feb 24, 2006·Pediatrics International : Official Journal of the Japan Pediatric Society·Selim KurtoğluNaci Topaloglu
Oct 17, 2009·Neurosurgery·Maryam Rahman, William A Friedman
Jan 9, 2015·American Journal of Therapeutics·Sunggeun LeeDonald Baumstein
Jun 10, 2000·Clinical Endocrinology·D M SmithC J Thompson
Sep 29, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·D DocciC Feletti
Jun 11, 2004·Journal of Intensive Care Medicine·T J VachharajaniK D Abreo
Dec 6, 2012·Neurocritical Care·Matthew A KirkmanDoris Doberenz
Jan 13, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Alberto BettinelliMario G Bianchetti
Apr 9, 2021·Wellcome Open Research·Usha K MisraUNKNOWN Tuberculous Meningitis International Research Consortium
Jan 25, 2008·Journal of the American Society of Nephrology : JASN·Richard H Sterns, Stephen M Silver
Nov 20, 2002·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Francesc Roca-RibasClara Llubiá
Dec 22, 2005·Journal of Neurosurgical Anesthesiology·Martin TisdallMartin Smith
Mar 14, 2014·Cell Biochemistry and Biophysics·Lizhao ChenLunshan Xu
Nov 28, 2015·Journal of Neurosurgery. Pediatrics·Cydni N WilliamsSusan L Bratton
Apr 11, 2017·Journal of Intensive Care Medicine·Usha Kant MisraSanjeev Kumar Bhoi
Jul 14, 2017·Critical Care Medicine·Steven G Achinger, Juan Carlos Ayus
Feb 14, 2018·BMJ Case Reports·Tzy Harn ChuaKatie Wynne
Jul 7, 2018·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dattatraya MuzumdarDeopujari Chandrashekhar
Sep 14, 2004·The Pediatric Infectious Disease Journal·Shih-Ming HuangKai-Sheng Hsieh
Oct 24, 2007·Arquivos de neuro-psiquiatria·Ana P D CardosoEliana A Cintra
Jan 15, 2004·Indian Journal of Pediatrics·Rashna DassSunit Singhi
Nov 25, 2003·The Neurologist·Alejandro A Rabinstein, Eelco F M Wijdicks
Oct 1, 2013·The American Journal of Medicine·Joseph G VerbalisChristopher J Thompson
Jul 18, 2016·Journal of the Neurological Sciences·Usha K MisraRajesh K Singh
Mar 29, 2001·Annales Françaises D'anesthèsie Et De Rèanimation·D BraccoP Ravussin
Nov 22, 2007·The American Journal of Medicine·Joseph G VerbalisRichard H Sterns
Apr 13, 2010·Neurosurgery Clinics of North America·Alan H YeeEelco F M Wijdicks

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Cachexia

Cardiac cachexia is a syndrome associated with the progressive loss of muscle and fat mass. It most commonly affects patients with heart failure and can significantly decrease the quality of life and survival in these patients. Here is the latest research on cardiac cachexia.

Cachexia & Brown Fat

Cachexia is a condition associated with progressive weight loss due to severe illness. In cancer patients, it is proposed to occur as a result of tumor-induced energy wasting. Several proteins have been implicated in browning and depletion of white adipose tissue. Here is the latest research on cachexia and brown fat.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

The Veterinary Clinics of North America. Small Animal Practice
S P DiBartola
The Veterinary Clinics of North America. Small Animal Practice
S P DiBartola
© 2022 Meta ULC. All rights reserved