Validity and Reliability of Four Clinical Gait Measures in Patients with Multiple Sclerosis

International Journal of MS Care
Susan E BennettPaulette Niewczyk

Abstract

The gold standards for assessing ambulation are the Expanded Disability Status Scale (EDSS) and the Timed 25-Foot Walk (T25FW) test. In relation with these measures, we assessed the reliability and validity of four clinical gait measures: the Timed Up and Go (TUG) test, the Dynamic Gait Index (DGI), the 2-Minute Walk Test (2MWT), and the 6-Minute Walk Test (6MWT). Patient self-report of gait was also assessed using the 12-item Multiple Sclerosis Walking Scale (MSWS-12). Individuals 20 years or older with a diagnosis of multiple sclerosis (MS) and an EDSS score of 2.0 to 6.5 completed the MSWS-12, T25FW test, TUG test, DGI, 2MWT, and 6MWT. All the tests were repeated 2 weeks later at the same time of day to establish their reliability and concurrent validity. Predictive validity was established using the EDSS. Forty-two patients with MS were included. All measures showed high test-retest reliability. The TUG test, 2MWT, and 6MWT were significantly correlated with the T25FW test (Spearman ρ = -0.902, -0.919, and -0.905, respectively). The EDSS was also significantly correlated with all the walking tests. The MSWS-12 demonstrated the highest correlation to the EDSS (ρ = 0.788). The TUG test, the DGI, the 2MWT, and the 6MWT exhibit...Continue Reading

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Dec 20, 2017·Multiple Sclerosis : Clinical and Laboratory Research·Liesbet M Peeters
Feb 6, 2019·Journal of Neurology·Emanuele SpinaFiore Manganelli
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Nov 18, 2021·JMIR Formative Research·Pim van OirschotPeter Joseph Jongen

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