Validity of a CB-NAAT assay in diagnosing tuberculosis in comparison to culture: A study from an urban area of South India.

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Aishwarya RajLeesha Sharon

Abstract

•CB-NAAT performance compared in 831 suspected pulmonary and extrapulmonary suspected cases.•The conventional stained smear and CB-NAAT results were compared to the MGIT culture.•Sensitivity and specificity of CB-NAAT was 84.43% and 94.93%.•The rapid results from CB-NAAT confirms its use in the tuberculosis diagnostic algorithm.•The benefits of disease diagnosis and prevention outweighs the price tag of the CB-NAAT tests.•This is more so for the resource poor countries where the burden of the disease is high.

Methods Mentioned

BETA
Assay
PCR
biopsy
lavage

Software Mentioned

CB
Statistical Package for Social Sciences ( SPSS Statistics
NAAT
GeneXpert®
Nambiar

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