Validity of Quantitative Lymphoscintigraphy as a Lymphedema Assessment Tool for Patients With Breast Cancer

Annals of Rehabilitation Medicine
Ji-Na YooTae-Du Jung

Abstract

To evaluate the validity of quantitative lymphoscintigraphy as a useful lymphedema assessment tool for patients with breast cancer surgery including axillary lymph node dissection (ALND). We recruited 72 patients with lymphedema after breast cancer surgery that included ALND. Circumferences in their upper limbs were measured in five areas: 15 cm proximal to the lateral epicondyle (LE), the elbow, 10 cm distal to the LE, the wrist, and the metacarpophalangeal joint. Then, maximal circumference difference (MCD) was calculated by subtracting the unaffected side from the affected side. Quantitative asymmetry indices (QAI) were defined as the radiopharmaceutical uptake ratios of the affected side to the unaffected side. Patients were divided into 3 groups by qualitative lymphoscintigraphic patterns: normal, decreased function, and obstruction. The MCD was highest in the qualitative obstruction (2.76±2.48) pattern with significant differences from the normal (0.69±0.78) and decreased function (1.65±1.17) patterns. The QAIs of the axillary LNs showed significant differences among the normal (0.82±0.29), decreased function (0.42±0.41), and obstruction (0.18±0.16) patterns. As the QAI of the axillary LN increased, the MCD decreased. The...Continue Reading

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Citations

Jan 19, 2018·Lymphatic Research and Biology·Svend HvidstenJane A Simonsen
Jul 26, 2017·Plastic and Reconstructive Surgery. Global Open·Navid M ToyserkaniJens A Sørensen
Aug 15, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·I-Wen PennTien-Yow Chuang
Sep 7, 2020·Advanced Drug Delivery Reviews·Anna K Polomska, Steven T Proulx

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Methods Mentioned

BETA
dissection

Software Mentioned

Xeleris
SPSS

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