PMID: 6397765Sep 1, 1984Paper

Validity of syphilis serodiagnosis in its prevention in apparently healthy workers applying for health certificates according to Law No. 837 of 25 July 1956

Quaderni Sclavo di diagnostica clinica e di laboratorio
G Barghini, M Perini Tavaroni

Abstract

The law 837/1956 establishes the right to subject the applicants for a certificate of health to serological tests for syphilis. Two Ministerial decrees establish that the first laboratory should carry out these tests using a fast test (VDRL) and should use the Complement fixation test as a control. This criterion of research does not correspond to the aims of the law. In fact the Complement fixation tests are not very sensitive and specific when used on the unknown luetic population. The positive diagnosis can be formulated by the first laboratory only using more sensitive and specific tests. The control laboratory, in this case, has succeeded in singling out the true luetics by using different serological tests (FTA-ABS, TPI).

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