PMID: 9172275Apr 18, 1997Paper

Validity of the family history method for identifying schizophrenia-related disorders

Psychiatry Research
G LiK L Davis

Abstract

We examined the family history method's validity for identifying schizophrenia related disorders (SRD) by comparing family history and family study derived diagnoses. First degree relatives (n = 284) of 48 psychiatrically disordered probands, predominantly with schizophrenia, were diagnosed using the Family History RDC (FH-RDC) which include three psychotic schizophrenia related disorders (P-SRD): schizophrenia, chronic SAD and chronic unspecified functional psychosis (CUFP). Supplementary criteria for schizophrenia related personality disorders (SRP), derived to identify schizotypal and paranoid personality disorders (PD), were also assessed. About two thirds of these relatives (n = 196; 69.0%) were independently diagnosed by RDC and DSM-III-R on both axis I and axis II in a family study. The specificity was 1.0 (178/178) and the sensitivity of the family history derived diagnosis for P-SRD was 0.72 (13/18). Sensitivity for P-SRD was improved, however, by inclusion of SRP which captured three of the five false negative relatives. The sensitivity of SRP for schizotypal or paranoid PD was 0.39 (15/38) and the specificity was 0.92 (127/138). The FH-RDC have moderately good sensitivity and excellent specificity for the psychotic s...Continue Reading

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Citations

Jun 23, 2010·Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors·Jarrod M EllingsonNicholas G Martin
Jul 18, 2012·Psychological Assessment·Guillermo Perez AlgortaRobert L Findling
Dec 26, 2006·European Psychiatry : the Journal of the Association of European Psychiatrists·Jochen Hardt, Petra Franke
Oct 15, 2019·International Journal of Nursing Practice·Rujnan Tuna, Birsen Dalli
Dec 29, 1998·The Journal of Nervous and Mental Disease·N M DochertyS W Gordinier

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