Validity, reliability and cut-offs of the Patient Health Questionnaire-9 as a screening tool for depression among patients living with epilepsy in Rwanda

PloS One
Fidele SeberaPeter Dedeken

Abstract

Patients with epilepsy (PwE) have an increased risk of active and lifetime depression. Two in 10 patients experience depression. Lack of trained psychiatric staff in low- and middle-income countries (LMIC) creates a need for screening tools that enable detection of depression in PwE. We describe the translation, validity and reliability assessment of the Patient Health Questionnaire-9 (PHQ-9) as a screening tool for depression among PwE in Rwanda. PHQ-9 was translated to Kinyarwanda using translation-back translation and validated by a discussion group. For validation, PwE of ≥15 years of age were administered the PHQ-9 and Hamilton Depression Rating Scale (HDRS) by trained psychiatry staff at Visit 1. A random sample of 20% repeated PHQ-9 and HDRS after 14 days to assess temporal stability and intra-rater reliability. Internal structure, reliability and external validity were assessed using confirmatory factor analysis, reliability coefficients and HDRS-correlation, respectively. Maximal Youden's index was considered for cut-offs. Four hundred and thirty-four PwE, mean age 30.5 years (SD ±13.3), were included of whom 33.6%, 37.9%, 13.4%, and 15.1% had no, mild, moderate and severe depression, respectively. PHQ-9 performed well...Continue Reading

References

Jul 1, 1994·The Journal of Clinical Investigation·J B WatsonD F Mosher
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Sep 26, 2001·Nursing Research·P S JonesK B Jaceldo
Feb 5, 2002·European Archives of Psychiatry and Clinical Neuroscience·J B Williams
Jan 18, 2003·Research in Nursing & Health·Cheryl Tatano BeckRobin D Froman
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Mar 12, 2004·Primary Care Companion to the Journal of Clinical Psychiatry·Lawson WulsinJeffery Heck
Nov 24, 2005·The Journal of Head Trauma Rehabilitation·Jesse R FannNancy Temkin
Dec 27, 2005·General Hospital Psychiatry·Alexandra MartinElmar Braehler
Jul 1, 2006·Journal of General Internal Medicine·Frederick Y HuangRobert L Spitzer
Dec 28, 2006·Neurology·Eylert Brodtkorb, Marco Mula
Sep 18, 2007·Journal of General Internal Medicine·Simon GilbodyCatherine Hewitt
Dec 15, 2007·Biostatistics·Jerome FriedmanRobert Tibshirani
Jun 24, 2008·BMC Psychiatry·Manote LotrakulRatana Saipanish
Nov 26, 2008·Journal of General Internal Medicine·Patrick O MonahanClaris Ojwang
Aug 14, 2010·BMC Health Services Research·Kirsten M van Steenbergen-WeijenburgChristina M van der Feltz-Cornelis
Feb 1, 2011·Psychiatry Research·Goran TrajkovićJelena Marinković
Oct 5, 2011·Archives of General Psychiatry·Christopher H WarnerCharles Hoge
Dec 21, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Laura ManeaDean McMillan
Jul 5, 2012·BMC Psychiatry·Takeshi InoueTsukasa Koyama
Nov 24, 2012·Neurology·Kirsten M FiestNathalie Jette
Dec 5, 2012·Annals of Medical and Health Sciences Research·Io OnwuekweJu Ejekwu
Jun 14, 2013·Journal of Affective Disorders·Mark ZimmermanKristy Dalrymple
Jul 11, 2014·Epilepsy & Behavior : E&B·Emily B LeafferCharles Begley
Jul 19, 2014·Indian Journal of Psychological Medicine·Jagdish R VankarHimanshu Sharma
Jul 22, 2014·Journal of Clinical Neurology·Oh-Young Kwon, Sung-Pa Park
Jul 30, 2014·Epilepsy & Behavior : E&B·Jaivir S RathoreGeorge E Tesar
Aug 6, 2014·Journal of General Internal Medicine·Linda G MarcEniko Edit Akom
Aug 30, 2014·Epilepsia·Kirsten M FiestNathalie Jetté
Nov 26, 2014·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Jose Hernández-PadillaJose Granero-Molina

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