Value of attenuation correction in stress-only myocardial perfusion imaging using CZT-SPECT

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Joris D van DijkPieter L Jager

Abstract

Attenuation correction (AC) improves the diagnostic outcome of stress-only myocardial perfusion imaging (MPI) using conventional SPECT. Our aim was to determine the value of AC using a cadmium zinc telluride-based (CZT)-SPECT camera. We retrospectively included 107 consecutive patients who underwent stress-optional rest MPI CZT-SPECT/CT. Next, we created three types of images for each patient; (1) only displaying reconstructed data without the CT-based AC (NC), (2) only displaying AC, and (3) with both NC and AC (NC + AC). Next, two experienced physicians visually interpreted these 321 randomized images as normal, equivocal, or abnormal. Image outcome was compared with all hard events over a mean follow-up time of 47.7 ± 9.8 months. The percentage of images interpreted as normal increased from 45% using the NC images to 72% using AC and to 67% using NC + AC images (P < .001). Hard event hazard ratios for images interpreted as normal were not different between using NC and AC (1.01, P = .99), or NC and NC + AC images (0.97, P = .97). AC lowers the need for additional rest imaging in stress-first MPI using CZT-SPECT, while long-term patient outcome remained identical. Use of AC reduces the need for additional rest imaging, decrea...Continue Reading

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Citations

Feb 27, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Thomas A Holly
Feb 28, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jei-Yie HuangYen-Wen Wu
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Aug 20, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·J D van DijkP L Jager
Apr 18, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fadi G Hage, Wael A AlJaroudi
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Jul 6, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Ora IsraelF Giammarile
May 19, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ernest V Garcia
Aug 26, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Brian G AbbottR Glenn Wells
Jun 21, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Piotr J SlomkaGuido Germano
Apr 10, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Gabriel Blacher Grossman
May 26, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jenny OddstigCecilia Hindorf
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Apr 15, 2020·Seminars in Nuclear Medicine·Eve PiekarskiDominique Le Guludec

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