PMID: 16628274Apr 22, 2006Paper

Value of diagnostic tools for myocardial ischemia used in routine clinical practice to predict cardiac events in patients with type 2 diabetes mellitus: a prospective study

Arquivos brasileiros de endocrinologia e metabologia
Mirela J de AzevedoJorge L Gross

Abstract

To analyze tests used in routine clinical practice for the diagnosis of myocardial ischemia to predict the development of cardiac events in type 2 diabetic patients. The occurrence of cardiac events (new myocardial infarct, myocardial re-vascularization procedures, congestive heart failure, acute pulmonary edema, sudden death, and death after myocardial infarction or pulmonary edema) were prospectively assessed in a cohort of 135 type 2 diabetic patients after up to seven years of follow-up. At baseline, coronary artery disease was assessed by the WHO cardiovascular questionnaire, resting electrocardiogram, and stress myocardial scintigraphy. Forty-eight cardiac events were observed in 41 patients (10.5 events/100 patients-year). In a Cox's proportional-hazard model only the presence of symptoms of coronary artery disease on the WHO cardiovascular questionnaire alone (RR = 2.13, 95% CI 1.11-4.07, P= 0.022) or in combination with abnormalities on resting ECG (RR= 2.03, 95% CI 1.05-3.92, P= 0.034) or on myocardial scintigraphy (RR= 1.89, 95% CI 1.001-3.57, P= 0.050) predicted cardiac events, adjusted for fasting plasma glucose, mean blood pressure, body mass index, peripheral vascular disease and diabetic nephropathy. The WHO car...Continue Reading

References

May 1, 1997·The New England Journal of Medicine·A P BurkeR Virmani
Sep 10, 1999·Diabetes Care·B Janand-DelenneV Lassmann-Vague
Jan 31, 2003·The New England Journal of Medicine·Peter GaedeOluf Pedersen
Dec 25, 2003·Diabetes Care·Mark E MolitchUNKNOWN American Diabetes Association

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Citations

Dec 4, 2013·Diabetology & Metabolic Syndrome·Luís Henrique CananiJorge Luiz Gross
Jul 12, 2011·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Thais SteemburgoJosé Alfredo Martínez
Jul 12, 2014·Atherosclerosis·Ana Luiza Teixeira dos SantosThemis Zelmanovitz
Nov 7, 2009·Arquivos brasileiros de endocrinologia e metabologia·Cristina TrichesMirela Jobim de Azevedo

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