Value of diffusion-weighted imaging for diagnosing vertebral metastases due to prostate cancer in comparison to other primary tumors

RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
T HackländerH Mertens

Abstract

Several publications have reported that the apparent diffusion coefficient is generally lower in metastatically affected vertebrae. Therefore, metastases are represented in diffusion-weighted images by increased signal intensity in comparison to unaffected vertebrae. However, there were indications that metastases due to prostate cancer may differ from this. Therefore, the contrast behavior of vertebral metastases due to prostate cancer or tumors with another histology are to be systematically studied using diffusion-weighted images. The present study is intended to examine whether the two groups differed and whether possible differences depended on the degree of sclerosis. In a retrospective study the vertebral metastases of patients with prostate cancer (n = 18) were compared to those of patients with tumors of another histology (n = 20). A steady-state free precession sequence was used for the diffusion-weighted imaging. Additionally, a T1 weighted sequence before and after administration of contrast agent as well as a fat suppressed T2 weighted sequence were performed. The contrast behavior of the metastases was evaluated for all four sequences and was compared to that of the unaffected parts of the vertebra. In 18 patients...Continue Reading

Citations

Oct 24, 2007·Neuroradiology·Christina PlankMajda M Thurnher
Jun 18, 2010·European Radiology·Andreas BiffarOlaf Dietrich
Mar 14, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·G PozziA Zerbi
Dec 20, 2007·Current Opinion in Urology·John KurhanewiczFergus Coakley
Dec 10, 2009·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Andrea Baur-Melnyk
Aug 26, 2014·AJR. American Journal of Roentgenology·Ty K SubhawongLaura M Fayad
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Apr 13, 2010·European Journal of Radiology·Andreas BiffarAndrea Baur-Melnyk
Jan 10, 2018·European Radiology·Frederic Carsten SchmeelGuido Matthias Kukuk
Oct 21, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jibin CaoLingling Cui

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