Value of EUS in Determining Curative Resectability in Reference to CT and FDG-PET: The Optimal Sequence in Preoperative Staging of Esophageal Cancer?

Annals of Surgical Oncology
L M A SchreursJ Th M Plukker

Abstract

The separate value of endoscopic ultrasonography (EUS), multidetector computed tomography (CT), and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the optimal sequence in staging esophageal cancer has not been investigated adequately. The staging records of 216 consecutive operable patients with esophageal cancer were reviewed blindly. Different staging strategies were analyzed, and the likelihood ratio (LR) of each module was calculated conditionally on individual patient characteristics. A logistic regression approach was used to determine the most favorable staging strategy. Initial EUS results were not significantly related to the LRs of initial CT and FDG-PET results. The positive LR (LR+) of EUS-fine-needle aspiration (FNA) was 4, irrespective of CT and FDG-PET outcomes. The LR+ of FDG-PET varied from 13 (negative CT) to 6 (positive CT). The LR+ of CT ranged from 3-4 (negative FDG-PET) to 2-3 (positive FDG-PET). Age, histology, and tumor length had no significant impact on the LRs of the three diagnostic tests. This study argues in favor of PET/CT rather than EUS as a predictor of curative resectability in esophageal cancer. EUS does not correspond with either CT or FDG-PET. LRs of FDG-PET were substanti...Continue Reading

References

Nov 23, 2000·The Journal of Thoracic and Cardiovascular Surgery·P FlamenL Mortelmans
Dec 26, 2001·Surgical Oncology·M Pera, M Pera
Nov 7, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S SieslingUNKNOWN Working Group of The Netherlands Cancer Registry
Mar 19, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D M ClementsT J Havard
Jul 13, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Patrick ReinartzUlrich Buell
Sep 15, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H L van WestreenenJ Th M Plukker
Dec 30, 2004·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Henderik L van WestreenenJohn Th M Plukker
Apr 1, 2005·Medical Decision Making : an International Journal of the Society for Medical Decision Making·A Cecile J W JanssensEwout W Steyerberg
Apr 20, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Rachel Bar-ShalomOra Israel
Nov 22, 2005·Journal of Surgical Oncology·Manuel PeraLuis Grande
Mar 28, 2006·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Hossein JadvarPeter S Conti
Sep 29, 2007·The British Journal of Surgery·H L van WestreenenJ T M Plukker

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Citations

Jun 14, 2012·Surgical Endoscopy·M van ZoonenF P Vleggaar
Jan 1, 2013·Current Radiology Reports·Johannes CzerninKen Herrmann
Mar 5, 2013·Surgical Oncology Clinics of North America·Charles R Mulligan
Oct 25, 2013·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R DhuparW L Hofstetter
Sep 19, 2015·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·T C FangK S Dua
Jan 13, 2012·Orvosi hetilap·László CzakóAttila Szepes
Jan 24, 2020·BMC Medical Imaging·Styliani MantziariMarkus Schäfer
Jun 20, 2017·Scandinavian Journal of Gastroenterology·Haitao ShiJie Wu
Sep 2, 2017·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·A OkamuraK Chin
Sep 12, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Jia GuoJinrong Qu
Feb 14, 2021·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Philipp LindeCarsten Kobe
May 29, 2021·The Surgical Clinics of North America·Ealaf Shemmeri, Thomas Fabian

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Methods Mentioned

BETA
surgical resection
sedation

Software Mentioned

PLUS
SPSS

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