Value of hepatic elastography and Doppler indexes for predictions of esophageal varices in liver cirrhosis

Medical Ultrasonography
Adriana BintintanPetru Adrian Mircea

Abstract

Non-invasive methods are required to diagnose presence and grading of esophageal varices in patients with hepatic cirrhosis and in this respect we have evaluated the role of transient elastography and abdominal ultrasound parameters. Cirrhotic patients were prospectively evaluated by transient elastography and Doppler ultrasound for diagnosis of presence and grading of esophageal varices, the results being compared with the findings of the esophagogastroduodenoscopy. Sixty patients with hepatic cirrhosis were analysed. The parameters that reached statistical significance for diagnosis of esophageal varices were: liver stiffness (LSM) > 15 kPa, hemodynamic liver index (PVr1) >/= 0.66, portal vascular resistance (PVR) > 17.66 and splenoportal index (SPI) > 4.77. The only parameter that reached statistical power for the diagnosis of large esophageal varices was LSM at a cut-off value of 28.8 kPa. Assessment of LSM in patients with liver cirrhosis can predict both the presence of esophageal varices and of large esophageal varices. The PVr1, PVR and SPI Doppler indexes can be used to diagnose the presence of esophageal varices but have no role in the prediction of large esophageal varices. Further studies are required to confirm the...Continue Reading

Citations

Sep 1, 2017·Expert Review of Gastroenterology & Hepatology·Davide RoccarinaEmmanuel A Tsochatzis
Jul 23, 2016·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Tao LiLei Wang
Jan 29, 2019·World Journal of Gastroenterology : WJG·Rafael PaternostroTheresa Bucsics
Dec 14, 2018·Current Hepatology Reports·Thomas ReibergerMattias Mandorfer
Mar 5, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Todd ChapmanRichard G Barr
Sep 28, 2021·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Masashi HirookaYoichi Hiasa

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