Value of hospital antimicrobial stewardship programs [ASPs]: a systematic review

Antimicrobial Resistance and Infection Control
Dilip NathwaniClaudie Charbonneau

Abstract

Hospital antimicrobial stewardship programs (ASPs) aim to promote judicious use of antimicrobials to combat antimicrobial resistance. For ASPs to be developed, adopted, and implemented, an economic value assessment is essential. Few studies demonstrate the cost-effectiveness of ASPs. This systematic review aimed to evaluate the economic and clinical impact of ASPs. An update to the Dik et al. systematic review (2000-2014) was conducted on EMBASE and Medline using PRISMA guidelines. The updated search was limited to primary research studies in English (30 September 2014-31 December 2017) that evaluated patient and/or economic outcomes after implementation of hospital ASPs including length of stay (LOS), antimicrobial use, and total (including operational and implementation) costs. One hundred forty-six studies meeting inclusion criteria were included. The majority of these studies were conducted within the last 5 years in North America (49%), Europe (25%), and Asia (14%), with few studies conducted in Africa (3%), South America (3%), and Australia (3%). Most studies were conducted in hospitals with 500-1000 beds and evaluated LOS and change in antibiotic expenditure, the majority of which showed a decrease in LOS (85%) and antib...Continue Reading

References

Feb 16, 2000·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·C A GentryM M Huycke
Feb 17, 2000·The Annals of Pharmacotherapy·L FrighettoP J Jewesson
Mar 7, 2000·The Journal of Antimicrobial Chemotherapy·F A Al-EidanJ B McConnell
Aug 2, 2000·Journal of Clinical Microbiology·J BarenfangerT Troutt
Jul 5, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R GrossN O Fishman
Aug 30, 2001·Archives of Internal Medicine·D H SolomonJ Avorn
Feb 27, 2003·The Medical Journal of Australia·Michael SouthMichael Starr
Mar 8, 2003·The Journal of Hospital Infection·S Saizy-CallaertC Chouaïd
Jul 12, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Carlos BantarMaría Eugenia Oliva
Aug 28, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anthony LaRocco
Sep 27, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Philip CarlingMichael Barza
Jan 17, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sigmund RüttimannHeiner C Bucher
Mar 27, 2004·The Journal of Antimicrobial Chemotherapy·Paul P CookRonald E Polk
Feb 8, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lou Ann Bruno-MurthaDeborah Zucker
Aug 30, 2005·QJM : Monthly Journal of the Association of Physicians·C M McLaughlinR A Seaton
Oct 19, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jan Jelrik OosterheertMarc J M Bonten
Feb 16, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anucha ApisarnthanarakUNKNOWN Thammasart University Antibiotic Management Team
Mar 15, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Carla PhilmonEdward Goodman
Apr 11, 2006·American Journal of Respiratory and Critical Care Medicine·Mirjam Christ-CrainBeat Müller
Apr 20, 2006·Journal of the American Medical Informatics Association : JAMIA·Jessina C McGregorAnthony D Harris
Apr 20, 2006·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Forest W ArnoldJulio A Ramirez
Apr 26, 2006·The Journal of Antimicrobial Chemotherapy·Graeme N ForrestRichard A Venezia
Jul 27, 2006·The Journal of Antimicrobial Chemotherapy·Jean-Ralph ZaharPhilippe Lesprit
Apr 19, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Elizabeth D HermsenMark E Rupp
May 22, 2008·Pharmacy World & Science : PWS·Hui DingXuzhuang Shen
Aug 6, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Allison L AgwuChristoph U Lehmann
Mar 26, 2009·Military Medicine·Patrick J DanaherJason W Lane
Apr 30, 2009·The Journal of Antimicrobial Chemotherapy·Dominik MertzStefano Bassetti
Sep 4, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V C C ChengW H Seto
May 26, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anucha ApisarnthanarakUNKNOWN Thammasat University Antimicrobial Stewardship Team
Aug 6, 2010·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Koji MiyawakiNobuo Kurokawa
Oct 1, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Karri A BauerDebra A Goff
Dec 15, 2010·The New England Journal of Medicine·Michael E Porter
Apr 15, 2011·BMC Health Services Research·Ferrán Catalá-LópezAntoni Parada
Jul 12, 2011·International Journal of Clinical Pharmacy·Katherine DunnColm Bergin
Sep 10, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J TeoW Lee
Sep 13, 2011·Médecine et maladies infectieuses·S BevilacquaN Thilly
Jan 20, 2012·International Journal of Clinical Pharmacology and Therapeutics·Yu-Hsuan YenKuei-Ju Cheng
Mar 3, 2012·International Journal of Clinical Pharmacy·Lucas MagedanzRodrigo Pires dos Santos
Mar 16, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Harold C StandifordGraeme N Forrest
Mar 16, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·James R BeardsleyChristopher C Ohl

❮ Previous
Next ❯

Citations

Jul 16, 2019·Expert Opinion on Drug Safety·Nicola Principi, Susanna Esposito
May 13, 2020·Expert Review of Anti-infective Therapy·Zikria SaleemTahir Mehmood Khan
May 30, 2020·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·UNKNOWN Bundesverband Deutscher Krankenhausapotheker e. V. (ADKA)UNKNOWN Robert Koch-Institut, Geschäftsstelle der Kommission ART
Sep 20, 2020·American Journal of Clinical Pathology·Julia SapozhnikovBlake W Buchan
May 19, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Katherine E GoodmanAnthony D Harris
Feb 15, 2020·Nature Reviews. Microbiology·Alex van BelkumWilliam Michael Dunne
Jul 28, 2020·Journal of Medical Economics·Urszula Religioni, Teresa Pakulska
Sep 26, 2020·Revista Panamericana De Salud Pública = Pan American Journal of Public Health·Jennifer Hegewisch-TaylorGabriel Levy-Hara
Nov 28, 2019·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Seven Johannes Sam AghdassiTobias Siegfried Kramer
Jan 18, 2021·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Gizem Guner OzenenFerda Ozkinay
Jan 23, 2021·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Shinobu ImaiKiyohide Fushimi
Jan 7, 2021·Infection and Drug Resistance·Md Anwarul Azim MajumderMarquita Gittens-St Hilaire
Feb 17, 2021·Annual Review of Animal Biosciences·Noelle R NoyesRandall S Singer
Apr 1, 2021·The Journal of Antimicrobial Chemotherapy·F O'RiordanA Fleming
Apr 19, 2021·The Science of the Total Environment·Anh Q NguyenLong D Nghiem
May 27, 2021·Expert Review of Anti-infective Therapy·Zikria SaleemMuhammad Azmi Hassali
Jun 22, 2021·Journal of Global Antimicrobial Resistance·Myung Jin LeeUNKNOWN Korea Study Group for Antimicrobial Stewardship (KOSGAP)
Feb 18, 2020·JAC-antimicrobial Resistance·Daniel Kwame AfriyieR Andrew Seaton
Jul 29, 2021·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Jyotsna AgarwalManodeep Sen
Aug 8, 2021·Journal of Clinical Medicine·Silvia CorcioneFrancesco Giuseppe De Rosa
Oct 1, 2021·Expert Review of Anti-infective Therapy·Zia Ul MustafaSyed Shahzad Hasan
Oct 6, 2021·International Journal of Antimicrobial Agents·Yuki YoshikawaMichele Cecchini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Related Papers

Healthplan
S Lutz, S J Henkind
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
M RzewuskaJoint Programming Initiative on Antimicrobial Resistance (JPIAMR) Working Group on Behavioural Approaches to Antibiotic Stew
© 2022 Meta ULC. All rights reserved