Value of ovarian reserve testing before IVF: a clinical decision analysis

Human Reproduction
B W J MolF J Broekmans

Abstract

To assess the value of testing for ovarian reserve prior to a first cycle IVF incorporating patient and doctor valuation of mismatches between test results and treatment outcome. A decision model was developed for couples who were considering participation in an IVF programme. Three strategies were evaluated: (I) withholding IVF without prior testing, (II) testing for ovarian reserve, and then deciding on IVF treatment if ovarian reserve was estimated to be sufficient, and (III) treatment with IVF without prior ovarian reserve testing. The outcome considered was the birth of a child. The valuation of the combination of the strategy conducted and the outcome accomplished was expressed on a distress scale in units of 'IVF cycles that were performed in vain'. Correct treatment with IVF and correct withholding of IVF were considered to bring no distress. The distress of withholding IVF in case pregnancy occurred is consequently specified by the ratio of the expected distress after incorrect withholding IVF to the expected distress after incorrect performing IVF (distress ratio). We interviewed both patients and doctors to determine realistic estimates for this distress ratio. The value of testing for ovarian reserve depends strongl...Continue Reading

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Citations

Sep 17, 2009·Archives of Gynecology and Obstetrics·Tevfik Yoldemir, Ian S Fraser
Sep 15, 2007·Reproductive Biomedicine Online·Roberto Palermo
Apr 22, 2009·Human Reproduction Update·P DevroeyUNKNOWN Evian Annual Reproduction (EVAR) Workshop Group 2008
Apr 22, 2010·Current Opinion in Obstetrics & Gynecology·Simone L BroerFrank J M Broekmans
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Feb 19, 2011·Human Fertility : Journal of the British Fertility Society·Gerasimos Marinakis, Dimitrios Nikolaou
Mar 6, 2008·Human Fertility : Journal of the British Fertility Society·Abha MaheshwariSiladitya Bhattacharya
Oct 6, 2009·Human Fertility : Journal of the British Fertility Society·Ahmed GibreelNeil P Johnson
Feb 18, 2010·Reproductive Biomedicine Online·J A CastillaL Martínez
Jun 23, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Corine M KoopmansBen W J Mol
Jun 2, 2007·Obstetrics and Gynecology·David H BaradNorbert Gleicher
Nov 2, 2014·Epidemiology and Health·Jong-Myon Bae
Jul 13, 2007·Current Opinion in Obstetrics & Gynecology

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