PMID: 8587757Nov 1, 1995Paper

Value of quantitative salivary gland scintigraphy in the early stage of Sjögren's syndrome

Nuclear Medicine Communications
K H BohuslavizkiE Henze

Abstract

The aim of this study was to test the impact of quantitative salivary gland scintigraphy in patients with suspected Sjögren's syndrome. Thirteen patients with suspected Sjögren's syndrome were investigated. During clinical work-up, three had severe and four had mild Sjögren's syndrome, while six were normal. Quantitative salivary gland scintigraphy was performed using a standardized method. The normal data-base consisted of 172 patients without any evidence of salivary gland malfunction. Visual and quantitative comparisons of the patients' scintigrams were made. In the patients with severe Sjögren's syndrome, uptake was 0.10 +/- 0.04% and 0.09 +/- 0.03% in the parotid and submandibular glands respectively, confirming the visual diagnosis. In the patients without Sjögren's syndrome, concordance between the visual and quantitative evaluations could also be shown. In contrast, among the patients with mild Sjögren's syndrome, uptake was diminished (P < 0.05), amounting to 0.21 +/- 0.05% and 0.16 +/- 0.02% in the parotid and submandibular glands respectively, while visual analysis indicated normal parenchymatous function. In conclusion, quantitative salivary gland scintigraphy is essential for the reliable detection of parenchymatou...Continue Reading

Citations

Feb 20, 2004·Annals of Nuclear Medicine·Kazuya ShizukuishiTomio Inoue
Jun 5, 2002·Annals of Nuclear Medicine·Meryem KayaSakir Berkarda
Feb 5, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Chao MaShuyao Zuo
Mar 11, 2000·European Journal of Radiology·R Hanlon, S King
Apr 24, 2013·Thyroid : Official Journal of the American Thyroid Association·Jeong-Seok ChoiYoung-Mo Kim
Mar 9, 1999·Clinical Nuclear Medicine·G A HermannV Mayrin
Mar 5, 1999·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·K H BohuslavizkiM Clausen
Oct 13, 2009·The Cochrane Database of Systematic Reviews·Chao MaShuyao Zuo
Aug 15, 2014·Nuclear Medicine Communications·Chae Moon HongByeong-Cheol Ahn
Sep 10, 2003·Nuclear Medicine Communications·B K AdamsS Parkar
Nov 30, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C H KaoH R Chang

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