Value of shear-wave elastography in the diagnosis of symptomatic invasive lobular breast cancer

Clinical Radiology
Y T SimA Evans

Abstract

To investigate the contribution of shear-wave elastography (SWE) in diagnosing invasive lobular breast cancer (ILC) in symptomatic patients. A retrospective case-controlled study of 52 patients with ILC and 52 patients with invasive ductal cancer (IDC), matched for age and tumour size, was performed. Breast density and mammographic and greyscale ultrasound features were graded using Breast Imaging-Reporting and Data System (BI-RADS) classification by two radiologists, blinded to SWE and pathology findings. Forty-four benign lesions were also included. The sensitivity of SWE was assessed, using a cut-off value of 50 kPa for mean elasticity. Statistical significance was evaluated using Chi-square and Chi-square for trend tests. Mean age for both ILC and IDC groups was 67 years. Mean size for ILC was 44 mm and IDC was 37 mm. The sensitivity for detection of ILC and IDC for mammography, greyscale ultrasound, and SWE were 79% versus 87%, 87% versus 98%, 94% versus 100%, respectively. SWE had significantly higher sensitivities than mammography for the detection of both ILC and IDC (p = 0.012 and p = 0.001, respectively). SWE was not significantly more sensitive than greyscale ultrasound for the detection of either tumour type. Four (...Continue Reading

References

Feb 4, 1999·AJR. American Journal of Roentgenology·R S ButlerE Rubin
Feb 1, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P J KneeshawP J Drew
Jun 26, 2004·Breast Cancer Research and Treatment·Carla BoetesJelle O Barentsz
Dec 19, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Christopher I Li, Janet R Daling
Jan 27, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·January K Lopez, Lawrence W Bassett
May 28, 2010·Radiology·Alexandra AthanasiouSylvia Neuenschwander
Dec 3, 2010·Breast Cancer Research : BCR·Andrew EvansAlastair Thompson
Jun 18, 2011·Breast Cancer Research and Treatment·Jung Min ChangSeung Ja Kim

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Citations

Mar 29, 2016·The Breast : Official Journal of the European Society of Mastology·Andrew EvansSarah J Vinnicombe
Mar 24, 2016·The British Journal of Radiology·Elisabetta GiannottiAndrew Evans
Jan 25, 2020·Current Medical Imaging Reviews·Rajendaran VairavanVithyacharan Retnasamy
Nov 7, 2017·Ultrasound in Medicine & Biology·Rongrong GuoBaowei Fei

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