Value of T1 and T2 relaxation times from echoplanar MR imaging in the characterization of focal hepatic lesions

AJR. American Journal of Roentgenology
M A GoldbergP R Mueller

Abstract

The purpose of this study was to determine the value of echoplanar imaging in characterizing focal hepatic lesions on the basis of image-derived T1 and T2 relaxation times. Forty-six proven hepatic lesions were analyzed: 24 solid (21 metastases, three primary liver tumors) and 22 nonsolid (11 hemangiomas and 11 cysts). Mean lesion size (maximal length) was 4.0 (+/- 3.2) cm, and 16 of 46 lesions were less than 2.0 cm. A commercially available 1.5-T echoplanar-equipped MR scanner was used to obtain fat-suppressed, single-excitation (TR essentially infinite) axial images with a slice thickness of 10 mm. T1-weighted inversion recovery images (TE = 25 msec; TI = 100, 380, 600, or 800 msec) were acquired for 28 of 46 lesions, and T2-weighted spin-echo images (TE = 25, 50, 100, 75 or 150 msec) were acquired for 45 of 46 lesions. For each acquisition (i.e., each different TI or TE), the entire liver was imaged in a single breath-hold of 12 sec or less. The mean T1 was 1004 (+/- 234) msec for solid lesions, 1337 (+/- 216) msec for hemangiomas, and 3143 (+/- 1392) msec for cysts. Although the mean T1 of solid and nonsolid lesions differed (p < .004), overlap precluded the use of T1 as a discriminatory index. Mean T2 times were 80 (+/- 18...Continue Reading

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