Value of the serum I-FABP level for diagnosing acute mesenteric ischemia

Surgery Today
Murat GüzelCevat Yazıcı

Abstract

This study examined the feasibility of using the serum intestinal fatty acid binding protein (I-FABP) level for the early diagnosis of acute mesenteric ischemia, and investigated whether it contributes to the clinical decision-making process. Thirty patients diagnosed with acute mesenteric ischemia, 27 patients with other types of acute abdomen who presented with acute abdomen symptoms but were not diagnosed with acute mesenteric ischemia, and 20 healthy people were included in the study. Mesenteric ischemia was confirmed by a pathological evaluation in patients who underwent intestinal resection due to detection of mesenteric ischemia during surgery. There was no significant difference in the leukocyte counts and D-dimer levels between subjects with mesenteric ischemia and acute abdomen due to other causes (p > 0.05). There was a significant difference in the serum I-FABP level between these groups (p < 0.001). The I-FABP level is a more reliable parameter for diagnosing acute mesenteric ischemia compared to leukocytosis and D-dimer elevation.

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Citations

Mar 27, 2016·Critical Care Clinics·Nathan J Klingensmith, Craig M Coopersmith
Apr 12, 2016·ANZ Journal of Surgery·Rıdvan KuluErdogan Sozuer
May 31, 2015·Surgery Today·Kazumasa Orihashi
Oct 6, 2014·Orvosi hetilap·Olivér RoseroAttila Szijártó
Oct 25, 2016·American Journal of Surgery·Shokei MatsumotoMitsuhide Kitano
Aug 26, 2017·Clinical Chemistry and Laboratory Medicine : CCLM·Katell Peoc'hOlivier Corcos
Aug 1, 2018·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Jose Canceco, Elizabeth J Winokur
Feb 3, 2016·Current Opinion in Critical Care·Annika Reintam BlaserJoel Starkopf
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Jul 19, 2018·General Thoracic and Cardiovascular Surgery·Kazumasa Orihashi
Jan 21, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Andrew S MillerDanette Wright
Apr 19, 2019·International Journal of Surgery·Sualeh Muslim KhanMuhammad Akbar Agha
Sep 25, 2021·Scientific Reports·Alexandre NuzzoUNKNOWN SURVI (Structure d’URgences Vasculaires Intestinales) Research Group (French Intestinal Stroke Center)

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