Value of Vascular and Non-Vascular Pattern on Computed Tomography Perfusion in Patients With Acute Isolated Aphasia

Stroke; a Journal of Cerebral Circulation
Salvatore RudilossoÁngel Chamorro

Abstract

Acute onset aphasia may be due to stroke but also to other causes, which are commonly referred to as stroke mimics. We hypothesized that, in patients with acute isolated aphasia, distinct brain perfusion patterns are related to the cause and the clinical outcome. Herein, we analyzed the prognostic yield and the diagnostic usefulness of computed tomography perfusion (CTP) in patients with acute isolated aphasia. From a single-center registry, we selected a cohort of 154 patients presenting with acute isolated aphasia who had a whole-brain CTP study available. We collected the main clinical and radiological data. We categorized brain perfusion studies on CTP into vascular and nonvascular perfusion patterns and the cause of aphasia as ischemic stroke, transient ischemic attack, stroke mimic, and undetermined cause. The primary clinical outcome was the persistence of aphasia at discharge. We analyzed the sensitivity, specificity, positive and negative predictive values of perfusion patterns to predict complete clinical recovery and ischemic stroke on follow-up imaging. The cause of aphasia was an ischemic stroke in 58 patients (38%), transient ischemic attack in 3 (2%), stroke mimic in 68 (44%), and undetermined in 25 (16%). CTP sh...Continue Reading

References

Mar 20, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·R E HanlonA W Dromerick
Dec 28, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Matthew B MaasKaren L Furie
May 18, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·José G MerinoSteven Warach
Jul 9, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Ataman KoseAylin B Demir
Jan 12, 2016·Cerebrovascular Diseases·C DenierC Flamand-Roze
Mar 16, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Salvatore RudilossoÁngel Chamorro
Oct 21, 2017·Clinical Neurology and Neurosurgery·Gabriel CasellaElisabeth B Marsh
Nov 4, 2017·Stroke; a Journal of Cerebral Circulation·Shadi YaghiUNKNOWN American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and
Nov 14, 2017·The New England Journal of Medicine·Raul G NogueiraUNKNOWN DAWN Trial Investigators
Dec 9, 2017·European Radiology·Friederike AusteinThomas Lindner
Feb 14, 2018·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Salvatore RudilossoXabier Urra
Sep 22, 2018·Current Opinion in Neurology·Solène Moulin, Didier Leys
Oct 18, 2018·Journal of Neurology·Davide StramboP Michel
Feb 6, 2019·Neuroradiology·Anna KoopmanFrederick Meijer
Jul 7, 2019·Current Neurology and Neuroscience Reports·Felix C Ng, Bruce C V Campbell

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Citations

Jan 26, 2021·Journal of the American College of Emergency Physicians Open·Victoria ServenAndrew W Asimos
Mar 9, 2021·Stroke; a Journal of Cerebral Circulation·Álvaro García-TornelMarc Ribó
Feb 21, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Alicia Gonzalez-MartinezJosé Vivancos

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