Value, search, persistence and model updating in anterior cingulate cortex.

Nature Neuroscience
Nils KollingMatthew F S Rushworth

Abstract

Dorsal anterior cingulate cortex (dACC) carries a wealth of value-related information necessary for regulating behavioral flexibility and persistence. It signals error and reward events informing decisions about switching or staying with current behavior. During decision-making, it encodes the average value of exploring alternative choices (search value), even after controlling for response selection difficulty, and during learning, it encodes the degree to which internal models of the environment and current task must be updated. dACC value signals are derived in part from the history of recent reward integrated simultaneously over multiple time scales, thereby enabling comparison of experience over the recent and extended past. Such ACC signals may instigate attentionally demanding and difficult processes such as behavioral change via interactions with prefrontal cortex. However, the signal in dACC that instigates behavioral change need not itself be a conflict or difficulty signal.

References

Jan 1, 1990·Annual Review of Neuroscience·M I Posner, S E Petersen
Jan 1, 1995·Experimental Brain Research·D ThalerR E Passingham
Jan 1, 1995·Experimental Brain Research·Y C ChenR E Passingham
Jun 1, 2002·Science·Munetaka Shidara, Barry J Richmond
May 6, 2003·Journal of Cognitive Neuroscience·M F S RushworthR E Passingham
Aug 6, 2004·Journal of Neurophysiology·Kae NakamuraCarl R Olson
Feb 12, 2005·Brain : a Journal of Neurology·Lesley K Fellows, Martha J Farah
Jun 17, 2006·Nature·Nathaniel D DawRaymond J Dolan
Jun 20, 2006·Nature Neuroscience·Steven W KennerleyMatthew F S Rushworth
Aug 11, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Suzanne N HaberRoberta Calzavara
Aug 22, 2006·Nature Neuroscience·Peter H RudebeckMatthew F S Rushworth
Aug 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hyojung Seo, Daeyeol Lee
Aug 7, 2007·Nature Neuroscience·Timothy E J BehrensMatthew F S Rushworth
Jan 25, 2008·Neuron·René QuilodranEmmanuel Procyk
Aug 30, 2008·Journal of Cognitive Neuroscience·Steven W KennerleyJonathan D Wallis
Oct 30, 2008·Neuron·Xiao-Jing Wang
May 29, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Rogier B MarsMatthew F S Rushworth
Sep 29, 2009·Trends in Neurosciences·Michael W ColeMatthew Botvinick
Feb 15, 2011·Nature Neuroscience·Alberto BernacchiaXiao-Jing Wang
Jun 7, 2011·Nature Neuroscience·Benjamin Y HaydenMichael L Platt
Oct 19, 2011·Proceedings of the National Academy of Sciences of the United States of America·Todd A HareAntonio Rangel
Oct 22, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nathalie CamilleLesley K Fellows
Nov 1, 2011·Nature Neuroscience·Steven W KennerleyJonathan D Wallis
Jan 11, 2012·Nature Neuroscience·Laurence T HuntTimothy E J Behrens
Mar 17, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xinying Cai, Camillo Padoa-Schioppa
Apr 10, 2012·Nature Neuroscience·Ken-ichi Amemori, Ann M Graybiel
Apr 12, 2012·Science·Nils KollingMatthew F S Rushworth
Dec 12, 2012·Trends in Cognitive Sciences·Timothy E J BehrensStephen M Smith
Dec 12, 2012·Nature Neuroscience·Benedetto De MartinoRaymond J Dolan
Feb 1, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Chung-Hay Luk, Jonathan D Wallis
Feb 9, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Erie D BoormanTim E Behrens
Feb 15, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Miriam Cornelia Klein-FlüggeTimothy Edward John Behrens
Aug 9, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jill X O'ReillyMark G Baxter
Aug 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jill X O'ReillyMatthew F S Rushworth
Oct 22, 2013·Nature Neuroscience·Nandakumar S NarayananMark Laubach
Jan 10, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tommy C Blanchard, Benjamin Y Hayden

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Citations

Jan 6, 2017·ELife·Jacqueline SchollMatthew Fs Rushworth
Mar 1, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Pierre PougetVeit Stuphorn
Mar 18, 2017·Proceedings of the National Academy of Sciences of the United States of America·Annamarie W HuttunenMichael L Platt
Dec 13, 2016·Brain Structure & Function·R E RobertsA M Bronstein
Dec 18, 2016·Trends in Neurosciences·Farshad A MansouriMark J Buckley
Mar 22, 2018·Journal of Cognitive Neuroscience·Seng Bum Michael YooBenjamin Y Hayden
Dec 2, 2017·Nature Communications·Georgios K PapageorgiouMatthew F S Rushworth
May 13, 2018·Nature Reviews. Neuroscience·Dean MobbsPeter Dayan
Jul 5, 2018·Wiley Interdisciplinary Reviews. Cognitive Science·John D Medaglia
Mar 22, 2018·Annual Review of Neuroscience·Marco K WittmannMatthew F S Rushworth
Aug 3, 2018·Psychological Medicine·Karolina M LempertHelen Blair Simpson
Aug 25, 2018·PLoS Computational Biology·Massimo SilvettiTom Verguts
Sep 7, 2018·Behavioural Pharmacology·Bolton K H ChauTrevor T-J Chong
Jan 10, 2019·Journal of Neurophysiology·Blake S PorterDavid K Bilkey
Oct 28, 2018·Journal of Neurology, Neurosurgery, and Psychiatry·Campbell Le HeronMasud Husain
Aug 8, 2018·Social Cognitive and Affective Neuroscience·George ZacharopoulosDavid E J Linden
Jul 12, 2019·The British Journal of Radiology·Leo P Sugrue, Rahul S Desikan
Jan 11, 2018·Translational Psychiatry·Funda AkkusGregor Hasler
Sep 28, 2016·Nature Neuroscience·R Becket Ebitz, Benjamin Yost Hayden
Aug 28, 2019·Brain Structure & Function·Edmund T Rolls
Oct 2, 2019·Nature Neuroscience·Elliot H SmithSameer A Sheth
Jan 15, 2020·Nature Human Behaviour·Eliana VassenaWilliam H Alexander
May 10, 2020·Social Cognitive and Affective Neuroscience·Kelsey R McDonaldScott A Huettel
Jun 26, 2020·Hippocampus·William de Cothi, Caswell Barry
Aug 1, 2020·PloS One·Ki Yun ParkEric C Leuthardt
Jul 18, 2020·The Journal of Comparative Neurology·Samantha M CalderazzoMaria Medalla
Nov 23, 2017·Frontiers in Human Neuroscience·Mariann OemischAnna Schubö
Apr 20, 2018·Brain : a Journal of Neurology·Campbell Le HeronMasud Husain
Apr 5, 2018·Frontiers in Neuroscience·Giancarlo La CameraBarry J Richmond
Sep 1, 2018·Proceedings of the National Academy of Sciences of the United States of America·Vickie LiChristopher Summerfield
Nov 14, 2018·Nature Communications·Patricia L LockwoodMatthew F S Rushworth
Mar 17, 2019·Cerebral Cortex·Kainan S Wang, Mauricio R Delgado
Apr 11, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Benjamin Y Hayden
Jul 4, 2019·Social Cognitive and Affective Neuroscience·Hannah U NohlenWilliam A Cunningham
Mar 7, 2020·Proceedings of the National Academy of Sciences of the United States of America·Adam T BrockettMatthew R Roesch

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