Valuing injection frequency and other attributes of type 2 diabetes treatments in Australia: a discrete choice experiment

BMC Health Services Research
Simon FiferDan Swain

Abstract

Multiple pharmacotherapy options are available to control blood glucose in Type 2 Diabetes Mellitus (T2DM). Patients and prescribers may have different preferences for T2DM treatment attributes, such as mode and frequency of administration, based on their experiences and beliefs which may impact adherence. As adherence is a pivotal issue in diabetes therapy, it is important to understand what patients value and how they trade-off the risks and benefits of new treatments. This study aims to investigate the key drivers of choice for T2DM treatments, with a focus on injection frequency, and explore patients' associated willingness-to-pay. A discrete choice experiment (DCE) was used to present patients with a series of trade-offs between different treatment options, injectable and oral medicines that were made up of 10 differing levels of attributes (frequency and mode of administration, weight change, needle type, storage, nausea, injection site reactions, hypoglycaemic events, instructions with food and cost). A sample of 171 Australian consenting adult T2DM patients, of which 58 were receiving twice-daily injections of exenatide and 113 were on oral glucose-lowering treatments, completed the national online survey. An error comp...Continue Reading

References

Apr 12, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·P T DonnanA D Morris
Jan 28, 2003·Health Services Research·Kathryn A PhillipsTara Maddala
Oct 11, 2011·Current Medical Research and Opinion·Mette BøgelundMorten Lammert
Jan 20, 2012·The Cochrane Database of Systematic Reviews·Uriëll L MalandaSandra D M Bot
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Oct 23, 2013·The Patient·Meryl BrodJens Harald Kongsø
Jan 15, 2015·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·A Brett HauberLarry Radican
Jun 8, 2015·Patient Education and Counseling·Maria Chiara RossiUNKNOWN BENCH-D Study Group

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Citations

Aug 18, 2020·Patient Preference and Adherence·Simon FiferSarah Richard
Jun 14, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Aude Roborel de ClimensAlka Shaunik
Jun 30, 2019·The Journal of Dermatological Treatment·Yukari OkuboYurie Taguchi
Nov 4, 2020·The Patient·Alison PearceStirling Bryan
Apr 22, 2021·Journal of Comparative Effectiveness Research·Laura Canals-RuizLuís Lizán

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Methods Mentioned

BETA
pharmacotherapy
PBAC

Software Mentioned

SPSS
NGene
Nlogit

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