Vanishing bile duct syndrome and Hodgkin disease: a case series and review of the literature

Journal of Pediatric Hematology/oncology
Amy Kun PassJudith F Margolin

Abstract

This is the first description in which the diagnosis of vanishing bile duct syndrome (VBDS) preceded the diagnosis of Hodgkin disease (HD) by several months, and for which patients received modifications to modern MOPP-ABV chemotherapy with successful clinical remission. VBDS is an uncommon form of liver disease manifested by severe cholestasis and progressive liver failure. We report 2 cases of stage IIIB pediatric HD and VBDS. Because VBDS is progressive and the only curative treatment is liver transplant, it is imperative to recognize that children with VBDS may also have concurrent HD.

References

Jul 15, 1990·Hospital Practice·J M Vierling, C D Howell
May 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N L BartlettS J Horning
Jan 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S G HubscherE Elias
Oct 1, 1994·Journal of Clinical Gastroenterology·C de GaloscyA P Geubel
Dec 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D MoradpourM Schmid
Aug 1, 1993·Seminars in Liver Disease·G M Woolf, J M Vierling
Apr 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·F GottrandJ P Farriaux
Jul 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·O M CrosbieJ E Hegarty
Mar 1, 2000·Digestive Diseases and Sciences·K KikuchiM Kako
Apr 14, 2000·Journal of Gastroenterology and Hepatology·M StrazzaboscoL Okolicsanyi
Apr 25, 2000·Journal of Pediatric Hematology/oncology·M A YusufS G Hübscher
Oct 6, 2000·São Paulo Medical Journal = Revista Paulista De Medicina·P A Lotufo
Oct 6, 2000·São Paulo Medical Journal = Revista Paulista De Medicina·M S RossiniC A Souza
Mar 10, 2001·Medical and Pediatric Oncology·A OzkanG Ozbay
Apr 16, 2002·European Journal of Gastroenterology & Hepatology·Suthat LiangpunsakulGeorge K Koukoulis
Sep 5, 2002·International Journal of Cancer. Journal International Du Cancer·Majida JalboutLotfi Chouchane
Dec 1, 1962·Archives of Internal Medicine·B A BOURONCLEA G VAZQUES
Aug 4, 2004·The Journal of Pediatrics·M TaghianE Jacquemin
Dec 22, 2004·The Journal of Experimental Medicine·Catherine M BollardHelen E Heslop
Mar 11, 2005·Journal of Clinical Gastroenterology·Mario StrazzaboscoCarlo Spirli
Aug 2, 2006·Clinical Lymphoma & Myeloma·Stefan K BartaPaul A Hamlin

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Citations

Jan 18, 2013·World Journal of Gastroenterology : WJG·Ana Paula OppenheimerCaryn G Morse
Nov 8, 2013·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Aamer AleemAbdulmalik Al-Sheikh
Nov 5, 2013·The Kaohsiung Journal of Medical Sciences·Kiong-Ming WongHsin-Ling Yin
Aug 2, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Shuichi TeraoKen Haruma
Jan 28, 2017·World Journal of Gastroenterology : WJG·Mena BakhitAnnMarie Liapakis

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