Variability in Treatment of Post-coarctectomy Hypertension: A Multicenter Study

Pediatric Cardiology
Brady S Moffett, Daniel J Penny

Abstract

Many pharmacologic therapies are available for treatment of post-coarctectomy hypertension in pediatric patients, which may lead to variability in care. Evaluation of trends in pharmacotherapy is necessary to evaluate quality of care. The Pediatric Health Information System database was queried from 2004 to 2013 for patients >30 days of age who had an ICD-9 code for coarctation of the aorta repair of coarctation by end-to-end anastomosis and had a RACHS-1 score of 2. Patients were excluded if they were admitted for >30 days, underwent mechanical circulatory support, or expired during the admission. Patient demographic and hospital data were collected along with antihypertensive pharmacotherapy. Trends in antihypertensive, analgesic, and sedative pharmacotherapy were evaluated, and multivariable statistical analysis was used to determine variables that significantly influenced cost. A total of 1636 patients [66.6 % male, median age 1.5 years (IQR 0.31-5.3)] met study criteria. Patients received a median of 3 (IQR 2-4) antihypertensive medications for a median of 8 days (IQR 5-11). Intravenous antihypertensive therapy was prescribed for a median 3 days (IQR 2-5) and oral therapy for a median of 1 day (IQR 1-2). Antihypertensive t...Continue Reading

References

Nov 1, 1990·Critical Care Medicine·A Smerling, W M Gersony
May 9, 1985·The New England Journal of Medicine·S S GiddingA Rosenthal
Jan 1, 1983·Clinical and Experimental Hypertension. Part A, Theory and Practice·F FalloF Mantero
Jul 25, 1998·The American Journal of Cardiology·M D ParrishB Hobde
Jul 2, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kathryn Rouine-RappScott Soifer
Oct 10, 2003·Pediatric Cardiology·T A NakagawaD S Schneider
Nov 9, 2004·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Valerie A SchroederWilliam I Douglas
Jun 16, 2012·The Journal of Thoracic and Cardiovascular Surgery·Sara K PasqualiUNKNOWN Pediatric Heart Network Investigators
Jan 22, 2013·Cardiology in the Young·Sara K PasqualiMarshall L Jacobs
Feb 26, 2014·Pediatrics·Sara K PasqualiJennifer S Li

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Citations

May 19, 2017·World Journal for Pediatric & Congenital Heart Surgery·Peter P Roeleveld, Eline G Zwijsen

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