Variability of aortic valve calcification measurement with multislice spiral computed tomography

Investigative Radiology
Karl M RuhlAndreas H Mahnken

Abstract

We sought to assess the variability of aortic valve calcifications (AVCs) regarding the reconstruction window at different heart phases using multislice-spiral computed tomography. A total of 46 patients (26 men; mean age. 65 years) underwent AVC scoring with multislice-spiral computed tomography (12 x 0.75 mm, 120 kV, 133 mAseff). Image reconstruction was performed every 10% of the RR-interval (0-90%). AVC was quantified using Agatston score, calcium volume, and calcium mass. Images were assessed for least motion artifacts. Coefficients of variation and Wilcoxon test were calculated. AVC scores are lowest at 60% and highest at 0% of the RR-interval (P < 0.001). Mean coefficients of variation were 36.2% (Agatston score), 38.7% (calcium volume), and 32.9% (calcium mass). At 60% (50-70%). minimal motion artifacts and the lowest variability of the scores were found. AVC scores show large variability depending on the point of image reconstruction. Diastolic image reconstruction at 60% of the RR-interval is recommended.

References

Mar 15, 1990·Journal of the American College of Cardiology·A S AgatstonR Detrano
Mar 1, 1997·Journal of the American College of Cardiology·B F StewartC M Otto
Mar 23, 1999·European Radiology·C Rodrigo GasqueA Gonzalez Martinez
Aug 31, 2000·The New England Journal of Medicine·R RosenhekH Baumgartner
Apr 20, 2001·AJR. American Journal of Roentgenology·C R BeckerM F Reiser
Jul 11, 2002·The American Journal of Cardiology·Axel SchmermundUNKNOWN MUNICH Registry Study Group. Multislice Normal Incidence of Coronary Health
Sep 10, 2002·Investigative Radiology·Andreas H MahnkenRolf W Gunther
Oct 19, 2002·Academic Radiology·Matthew J BudoffKevin D O'Brien
Jul 31, 2003·The American Journal of Cardiology·David M ShavelleKevin D O'Brien
Oct 22, 2004·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·A H MahnkenR W Günther
Nov 18, 2004·AJR. American Journal of Roentgenology·Ralf KoosHarald Peter Kühl

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Citations

Dec 7, 2013·International Heart Journal·Soe Hee AnnHo-Joong Youn
Apr 24, 2007·AJR. American Journal of Roentgenology·Andreas H MahnkenRalf Koos
Sep 23, 2010·AJR. American Journal of Roentgenology·Hatem AlkadhiStephan Baumueller
Sep 22, 2009·Cardiology Clinics·Juan GaztanagaJavier Sanz

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