PMID: 9448617Feb 4, 1998Paper

Variable management of soft tissue sarcoma: regional audit with implications for specialist care

The British Journal of Surgery
R ClasbyC D Fletcher

Abstract

The aim of this study was to determine how and by which specialties patients with soft tissue sarcoma are investigated and treated within a single large health region and with what outcomes and implications for resource uptake. By retrieving the records of 377 patients with primary soft tissue sarcoma treated in the South-East Thames Region between 1986 and 1992, the presentation, investigation, treatment and outcome were compared with defined criteria for optimal management. Patient management was assessed and compared between specialties and districts on the basis of outpatient time, appropriate use of radiological investigations and preoperative biopsy, type of surgery, content of the pathology report and the incidence of local recurrence, metastasis and death over a mean follow-up period of 2.5 years. Most patients (53.6 per cent) were treated by general surgeons, irrespective of tumour location. Overall only 21.3 per cent of patients were investigated optimally with wide variation among specialties. Only 60.0 per cent were treated adequately (wide excision or surgery with radiotherapy). Uptake of adjunctive therapy and follow-up were variable. Outcome was poorer in patients having a marginal excision and recurrence. Invest...Continue Reading

References

Jun 1, 1987·The British Journal of Surgery·T DavidsonG Westbury
Jan 15, 1984·International Journal of Cancer. Journal International Du Cancer·M TrojaniC Lagarde
Jan 1, 1993·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J A van UnnikH T Mouridsen
Aug 3, 1996·Lancet·P SelbyR Haward

❮ Previous
Next ❯

Citations

Oct 26, 2005·Current Treatment Options in Oncology·R Lor RandallKaren H Albritton
Feb 9, 2008·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Luis A Pérez RomasantaUNKNOWN SEOR Sarcoma Group
Apr 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Gunar K Zagars, Matthew T Ballo
Jun 12, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·F BrounsI De Wever
Sep 27, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J GlencrossM W Reed
Mar 22, 2002·The Lancet Oncology·S SingerC D Fletcher
Jun 6, 2003·The Lancet Oncology·Matthew A Clark, J Meirion Thomas
Aug 19, 2005·The New England Journal of Medicine·Matthew A ClarkJ Meirion Thomas
Jun 4, 2008·Sarcoma·Lawrence PaszatEric Holowaty
Jun 4, 2008·Sarcoma·A A BhanguR J Grimer
Mar 1, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C R RossiI Ray-Coquard
Apr 18, 2000·Annals of Surgery·J J LewisM F Brennan
Apr 14, 2010·BMC Public Health·Giuseppe MastrangeloCarlo R Rossi
Dec 7, 2011·World Journal of Surgical Oncology·Akinobu NishimuraAkihiro Sudo
Dec 24, 2005·Annals of Surgical Oncology·Marco FioreAlessandro Gronchi
Feb 25, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Constance ThibaultYohann Loriot
Nov 9, 2015·Journal of Cancer Research and Clinical Oncology·Antonella BrunelloVittorina Zagonel
Jun 16, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M L E A Jansen-LandheerH Gelderblom
Mar 15, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Nicolas PenelJean-Yves Blay
Apr 20, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M A Clark, J M Thomas
Oct 27, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Berna Bozkurt DumanYaşar Sertdemir
Apr 25, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·V KainhoferA Leithner
Jun 21, 2016·PET Clinics·Ghassan El-Haddad
Jun 13, 2015·International Journal of Radiation Oncology, Biology, Physics·Elizabeth H BaldiniThomas F DeLaney
Apr 28, 1999·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N de Saint Aubain Somerhausen, C D Fletcher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
I Ray-CoquardJ-Y Blay
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
J GlencrossM W Reed
© 2021 Meta ULC. All rights reserved