Variable prevalence of pulmonary hypertension in patients with advanced interstitial pneumonia.

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Nevins W ToddSergei P Atamas

Abstract

Pulmonary hypertension may occur in patients with interstitial pneumonia and is associated with increased mortality. We sought to determine the prevalence of pulmonary hypertension in sub-groups of patients with interstitial pneumonia and to investigate possible associations between pulmonary vascular hemodynamics and pulmonary function. The presence or absence of pulmonary hypertension was assessed in 70 patients with advanced interstitial pneumonia who underwent right heart catheterization. The associations of pulmonary hypertension with clinical characteristics and pulmonary function tests were analyzed. The prevalence of pulmonary hypertension in patients with idiopathic interstitial pneumonia was 29% vs 64% in patients with connective tissue disease-interstitial pneumonia (p = 0.013). African American patients had a significantly higher prevalence of pulmonary hypertension in the entire study population (81% vs 22%, p < 0.001) and in the idiopathic interstitial pneumonia group (70% vs 19%, p < 0.01). Regression analyses revealed no association between mean pulmonary artery pressure (mPAP) and forced vital capacity or mPAP and diffusion capacity of the lung for carbon monoxide in the entire cohort or in sub-groups of patien...Continue Reading

References

Sep 7, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·T P M WhelanP S Dahlberg
Oct 21, 2005·Chest·Hassan F NadrousJay H Ryu
Jul 13, 2007·The European Respiratory Journal·A F ShorrS D Nathan
Sep 18, 2007·Chest·Nina M PatelSteven M Kawut
Oct 22, 2008·American Journal of Respiratory and Critical Care Medicine·Robin CondliffeJ Gerry Coghlan

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Citations

Apr 12, 2013·Medizinische Klinik, Intensivmedizin und Notfallmedizin·M Pfeifer
Jul 4, 2012·Heart Failure Clinics·Dana McGlothlin
Oct 29, 2011·The Medical Clinics of North America·Esam H Alhamad, Gregory P Cosgrove
Jul 16, 2013·International Journal of Cardiology·Charlotte U AndersenUlf Simonsen
Mar 20, 2012·Respiratory Medicine·Charlotte U AndersenElisabeth Bendstrup
Jun 17, 2011·Respiration; International Review of Thoracic Diseases·Georgia PitsiouDemosthenes Bouros
Jan 26, 2018·European Respiratory Review : an Official Journal of the European Respiratory Society·Laurent PlantierBruno Crestani
Jul 11, 2013·American Journal of Respiratory Cell and Molecular Biology·Irina G LuzinaSergei P Atamas
Oct 13, 2012·International Journal of Immunopathology and Pharmacology·D CastriaP Rottoli

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