Abstract
Angiographic coronary artery disease (CAD) was correlated with clinical features, electrocardiographic (ECG) findings and the results of medical management or aortocoronary bypass in 42 patients with angina at rest associated with transient ST segment elevation (variant angina). Patients were divided into three sub-sets based on the coronary arteriographic findings. On the basis of greater than 75% luminal diameter narrowing, 28 patients had multiple vessel, ten had single vessel and four had minimal (less than 50% narrowing) CAD. The angiographic sub-sets did not differ significantly in age, sex, coronary risk factors, time from onset of rest pain to coronary angiography, or in the presence of arrhythmias during ischaemic episodes. Patients with multiple vessel CAD more commonly had prior coronary events (P less than 0.01), an abnormal baseline ECG (P less than 0.05) or both (P less than 0.001). These features did not distinguish patients with single vessel from those with minimal CAD. ST elevation in the inferior leads during episodes of myocardial ischaemia was more common (P less than 0.005) in patients with minimal CAD. Twenty--four patients with multiple vessel and six with single vessel CAD underwent aortocoronary by-pas...Continue Reading
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