Variants and Unusual Patterns of Prostate Cancer

Surgical Pathology Clinics
Samson W Fine

Abstract

Beyond the typical acinar morphology observed in most prostatic adenocarcinoma, a spectrum of morphologic variants and prostate cancer subtypes exists. These unusual entities may be further classified into (1) cancer morphologies arising by divergent differentiation of prostatic ductal, acinar, or basal cells and associated with unique clinical features or therapeutic approaches, and (2) histologies occurring in the context of usual prostatic adenocarcinoma that may result in diagnostic misinterpretation or difficulties in Gleason grade assignment, especially in limited samples. This article details several variants, with emphasis on diagnostic criteria, differential diagnoses, and clinical significance.

References

Mar 1, 1979·The Journal of Urology·L F GreeneF M Tomera
Jun 1, 1979·Urology·A ElbadawiR A Cooper
Dec 1, 1992·The American Journal of Surgical Pathology·J I Epstein, O A Armas
Mar 1, 1992·The Journal of Urology·R J AmatoF H Dexeus
May 1, 1992·Journal of Clinical Pathology·O Ben-Izhak, C Lichtig
Jan 1, 1992·The American Journal of Surgical Pathology·M G WeaverA G Ayala
Oct 1, 1990·Histopathology·N WernertG Dhom
Sep 1, 1991·British Journal of Urology·R J CohenZ Haffejee
Apr 15, 1991·Cancer·W N ChristensenJ I Epstein
Apr 1, 1985·The American Journal of Surgical Pathology·J I Epstein, P H Lieberman
Jul 1, 1986·Cancer·L H SobinE B Helwig
Nov 1, 1986·The American Journal of Surgical Pathology·H D Feiner, R Gonzalez
Nov 1, 1986·The American Journal of Surgical Pathology·A Alguacil-Garcia
Jun 1, 1988·The American Journal of Surgical Pathology·J Y RoN G Ordóñez
Mar 1, 1989·Urology·R K Manne, F S Haddad
Apr 1, 1988·Human Pathology·W RemmeleP Harding
Dec 1, 1988·The American Journal of Surgical Pathology·J E McNealT A Stamey
Nov 1, 1987·The Journal of Urology·H Matzkin, Z Braf
May 1, 1987·The American Journal of Surgical Pathology·T N Moyana
Sep 1, 1987·The American Journal of Surgical Pathology·A R Schned
Jul 1, 1986·Journal of Clinical Pathology·M StrattonI A Lampert
Aug 1, 1985·The American Journal of Surgical Pathology·D G BostwickR V Rouse
Aug 1, 1973·Cancer·V E DubeL F Greene
Dec 1, 1971·The Journal of Urology·M M Melicow, M Tannenbaum
Jan 1, 1983·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·F FetissofP Jobard
Jul 1, 1981·The Journal of Urology·L I Giltman

❮ Previous
Next ❯

Citations

Apr 1, 2017·Current Oncology Reports·Panagiotis J VlachostergiosHimisha Beltran

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
D J Grignon
Analytical and Quantitative Cytopathology and Histopathology
Gregor Mikuz
© 2021 Meta ULC. All rights reserved