Variation in antimicrobial action of proanthocyanidins from Dorycnium rectum against rumen bacteria

Phytochemistry
Subathira SivakumaranMichael Tavendale

Abstract

The proanthocyanidin polymer fractions of the leaves of the forage legume Dorycnium rectum were analysed by acid catalysis with benzyl mercaptan, NMR and ES-MS. The results showed that D. rectum differs from other temperate proanthocyanidin-containing forage legumes in that the range of polymers extends up to very high degrees of polymerisation. Three fractions were characterised as low, medium, and high molecular weight proanthocyanidin fractions with mean degree of polymerisations of 10.3, 41 and 127, respectively. Epigallocatechin was the most abundant extension unit and the terminating flavan-3-ols comprised largely catechin and gallocatechin units in equal proportions. Formation of thiolyated dimer products showed the interflavan-linkages of the lower molecular weight proanthocyanidins to be predominantly C4-->C8 with a small amount of C4-->C6. ES-MS spectra distinguished lower from higher polymeric proanthocyanidins from M2- to M8(2)-. The antibacterial activity of proanthocyanidin fractions against pure cultures of microbes selected from the ruminal population to represent fibre degrading, proteolytic and hyper ammonia producing bacteria in broth culture was evaluated. The activity of proanthocyanidin fractions against C...Continue Reading

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Citations

Aug 11, 2006·Journal of Chemical Ecology·Subathira SivakumaranLucy P Meagher
May 22, 2013·Journal of Chemical Ecology·Rachel A StongDaniel K Manter
Feb 2, 2016·Journal of Pharmaceutical and Biomedical Analysis·Honorata M RopiakIrene Mueller-Harvey
Oct 9, 2007·Phytochemistry·Simone RochfortFrank R Dunshea
Jun 6, 2006·Phytochemical Analysis : PCA·Maarit KaronenKalevi Pihlaja
Sep 4, 2010·Journal of the Science of Food and Agriculture·Amlan K Patra, Jyotisna Saxena
Aug 13, 2013·Journal of the Science of Food and Agriculture·Martin M LorenzPeter Udén
Aug 31, 2016·Journal of Animal Physiology and Animal Nutrition·A L Abdalla FilhoH Louvandini
May 19, 2012·International Journal of Molecular Sciences·Lei YangYuangang Zu
Feb 12, 2017·Asian-Australasian Journal of Animal Sciences·Jinshun ZhanGuo Qi Zhao
Feb 9, 2008·Analytical Chemistry·Brandy J JohnsonFrances S Ligler

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