Abstract
We studied the relationship between changes in body composition and changes in blood pressure levels. The mechanisms underlying the frequently observed progression from pre-hypertension to hypertension are poorly understood. We examined 1,145 subjects from a population-based survey at baseline in 1994/1995 and at follow-up in 2004/2005. First, we studied individuals pre-hypertensive at baseline who, during 10 years of follow-up, either had normalized blood pressure (PreNorm, n = 48), persistently had pre-hypertension (PrePre, n = 134), or showed progression to hypertension (PreHyp, n = 183). In parallel, we studied predictors for changes in blood pressure category in individuals hypertensive at baseline (n = 429). After 10 years, the PreHyp group was characterized by a marked increase in body weight (+5.71% [95% confidence interval (CI): 4.60% to 6.83%]) that was largely the result of an increase in fat mass (+17.8% [95% CI: 14.5% to 21.0%]). In the PrePre group, both the increases in body weight (+1.95% [95% CI: 0.68% to 3.22%]) and fat mass (+8.09% [95% CI: 4.42% to 11.7%]) were significantly less pronounced than in the PreHyp group (p < 0.001 for both). The PreNorm group showed no significant change in body weight (-1.55% [9...Continue Reading
References
May 1, 1991·Annals of Epidemiology·J Stamler
May 1, 1983·Circulation·H B HubertW P Castelli
Aug 26, 1998·Journal of the American College of Cardiology·H W HenseH Schunkert
Aug 28, 1998·BMJ : British Medical Journal·M W MuschollH Schunkert
Dec 1, 2001·Lancet·R S VasanD Levy
Jan 17, 2002·The New England Journal of Medicine·R S VasanD Levy
Sep 17, 2003·Hypertension·Judith E NeterJohanna M Geleijnse
Oct 27, 2004·Archives of Internal Medicine·Kurt J GreenlundGeorge A Mensah
Dec 24, 2004·The New England Journal of Medicine·Lars SjöströmUNKNOWN Swedish Obese Subjects Study Scientific Group
Jun 29, 2005·Hypertension·Oscar H FrancoChris de Laet
Mar 16, 2006·The New England Journal of Medicine·Heribert Schunkert
Mar 16, 2006·The New England Journal of Medicine·Stevo JuliusUNKNOWN Trial of Preventing Hypertension (TROPHY) Study Investigators
Aug 1, 2006·Journal of Hypertension·Kyung Mook ChoiSeon Mee Kim
May 14, 2008·Hypertension·David W Harsha, George A Bray
Jul 16, 2008·Journal of Hypertension·Giuseppe ManciaRoberto Sega
Sep 23, 2008·Journal of Hypertension·Marcello Ricardo Paulista MarkusHeribert Schunkert
Jul 1, 2009·Hypertension·Franz H Messerli, Harikrishna Makani
Jul 1, 2009·Hypertension·Giuseppe ManciaRoberto Sega
Citations
Jun 6, 2013·Current Hypertension Reports·Mieczysław LitwinLidia Gackowska
Oct 1, 2011·Neurology·M LeeB Ovbiagele
Dec 15, 2015·Blood Pressure·Dagmara HeringKrzysztof Narkiewicz
Feb 14, 2013·Clinical and Experimental Hypertension : CHE·Sunjie YanSongjing Zhang
Dec 26, 2012·Hypertension·Mieczysław LitwinMieczysław Szalecki
Nov 22, 2018·European Heart Journal·Seryan AtasoyKarl-Heinz Ladwig
Jan 10, 2019·European Heart Journal·Ernesto L Schiffrin
Nov 8, 2014·Journal of Hypertension·Bo Carlberg
Feb 9, 2017·Journal of Hypertension·You-Cheol HwangEdward J Boyko
May 14, 2021·PloS One·Zhaoyang FanJunting Liu