PMID: 6713827Jan 1, 1984Paper

Variation in erythrocyte enzyme activity among primate species

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
T R TurnerH W Mohrenweiser

Abstract

Significant differences between species in the mean level of enzyme activity, ranging from 50 to 400%, were detected during a study of 10 enzymes from erythrocytes of humans and five non-human primates. The activity differences were consistent with variation, between species, at the structural loci for specific enzymes rather than differences in mean cell age, hemoglobin content or other pleiotropic effects. For seven of the eight loci at which direct comparisons among the six species could be made, the number of species-specific activity differences was greater than the number of variants observed by electrophoresis. Thus not only do activity measurements detect previously "hidden" variation among species but they also provide information regarding genetic differences which may be of potential physiological and/or selective relevance.

References

Jul 1, 1975·The Journal of Pediatrics·M Komazawa, F A Oski
Dec 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J W Harvey, J J Kaneko
Aug 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N S AgarJ Roberts
Aug 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N S AgarJ Roberts
Jan 1, 1976·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N S AgarJ D Harley
Apr 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·A MorelliA De Flora
Apr 1, 1978·Biochemical Genetics·F Bonhomme, R K Selander
Dec 1, 1975·British Journal of Haematology·P BoivinA Kahn
Aug 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N S AgarJ D Harley
Jan 1, 1974·Annals of Human Genetics·L C EzeD A Evans
Feb 1, 1970·Biochemical Genetics·N A Barnicot, P Cohen
May 1, 1983·American Journal of Physical Anthropology·N C DracopoliC J Jolly
Oct 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J V NeelM H Meisler
Aug 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·H W Mohrenweiser
Sep 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·H W Mohrenweiser, J V Neel
Aug 1, 1980·British Journal of Haematology·S MiwaN Ninomiya
Jan 16, 1965·Nature·J SMITHR A FREEDLAND

Citations

Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J M NaiduH W Mohrenweiser
Jan 1, 1985·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J M Naidu, H W Mohrenweiser
Nov 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·M KurataN S Agar
Jan 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·M KurataK Takeda

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.