Variation in hospitalizations and hospital length of stay in children with vaso-occlusive crises in sickle cell disease

Pediatric Blood & Cancer
Julie A PanepintoJ Paul Scott

Abstract

As a measure of morbidity of vaso-occlusive crises (VOC) in sickle cell disease, we used a national hospital discharge database, the Kids' Inpatient Database (KID), to determine the number of hospitalizations and hospital length of stay (LOS) by age. Nationally weighted hospital discharges for VOC in children with sickle cell disease were analyzed using data from 2,500 hospitals in the Healthcare Cost and Utilization Project (HCUP) KID. Number of discharges and hospital LOS by age group were analyzed. Multiple linear regression was performed to analyze the effect of age on hospital LOS. There were 20,271 hospital discharges for children with sickle cell disease and VOC. Mean age (SD) at time of admission was 10.6 (5.38) years with 49% being males. The overall average LOS was 4.4 days. There were differences in the number of hospital discharges by age group (P < 0.001). In addition, there was a difference in LOS by age group (P < 0.0001). After controlling for potential confounders, older age was associated with a longer LOS (P < 0.0001). Older children with sickle cell disease and VOC have increased hospitalizations and longer LOS. This age effect should be considered when measuring the effect of an intervention on hospital uti...Continue Reading

References

Jul 4, 1991·The New England Journal of Medicine·O S PlattT R Kinney
May 9, 1987·British Medical Journal·M BrozovićA I Brownell
Mar 1, 1980·The Journal of Clinical Investigation·D R PowarsS P Azen
Jun 1, 1996·The Journal of Pediatrics·J P ScottR J Labotka
Aug 8, 1996·The New England Journal of Medicine·M C WaltersK M Sullivan
Sep 11, 1997·The New England Journal of Medicine·H F Bunn
Oct 19, 1999·Journal of Pediatric Hematology/oncology·P J NietertM D Silverstein
Jan 13, 2000·The New England Journal of Medicine·S T MillerT R Kinney
Feb 9, 2000·Archives of Pediatrics & Adolescent Medicine·J R MeurerP Layde
Jan 5, 2002·Pediatrics·Heather T KeenanSusan L Bratton
Mar 5, 2003·Journal of Health Care for the Poor and Underserved·Michelle L MayerChristopher C Dvorak

❮ Previous
Next ❯

Citations

May 1, 2007·The Pediatric Infectious Disease Journal·Athena P KourtisDenise J Jamieson
Jan 18, 2011·Hematology·Wally R Smith, Marshall Scherer
Sep 25, 2010·Journal of Pain and Symptom Management·Samir K BallasUNKNOWN Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia
Apr 2, 2010·American Journal of Preventive Medicine·Wanda D BarfieldCarrie K Shapiro-Mendoza
Apr 2, 2010·American Journal of Preventive Medicine·Scott D GrosseSuzette O Oyeku
Aug 18, 2009·The American Journal of Emergency Medicine·Alex L RogovikRan D Goldman
Jul 6, 2007·Haemophilia : the Official Journal of the World Federation of Hemophilia·M D TarantinoR M Brusky
Apr 3, 2008·Pediatric Blood & Cancer·Jean L RaphaelBrigitta U Mueller
Dec 20, 2011·Pediatric Blood & Cancer·J A PanepintoD C Brousseau
Jan 10, 2012·Pediatric Blood & Cancer·Jean L RaphaelSuzette O Oyeku
Nov 16, 2012·Pediatric Blood & Cancer·Matthew P MyrvikJulie A Panepinto
Mar 23, 2011·Pediatric Blood & Cancer·Matthew P MyrvikJennifer L Butcher
Jul 27, 2010·Pediatric Blood & Cancer·Carlton DampierUNKNOWN Comprehensive Sickle Cell Centers (CSCC) Clinical Trial Consortium (CTC)
Nov 2, 2012·American Journal of Hematology·Amanda M BrandowJulie A Panepinto
Apr 16, 2011·Pediatric Blood & Cancer·John LeschkeDavid C Brousseau
Mar 2, 2011·Pediatric Blood & Cancer·Julie A WolfsonMichele D Kipke
Jan 13, 2011·Pediatric Blood & Cancer·Julie A WolfsonMichele D Kipke
Mar 4, 2011·Pediatric Blood & Cancer·Amanda M BrandowJulie A Panepinto
May 18, 2011·Pediatric Blood & Cancer·Jean L RaphaelThomas Giordano
Jan 21, 2014·Pediatric Blood & Cancer·Oluwakemi Badaki-MakunUNKNOWN Pediatric Emergency Care Applied Research Network (PECARN) Magnesium in Sickle Cell Crisis (MAGiC) Study Group
Oct 30, 2013·Pediatric Blood & Cancer·Amanda M BrandowJulie A Panepinto
Aug 2, 2015·Blood·David C BrousseauUNKNOWN Pediatric Emergency Care Applied Research Network (PECARN)
Aug 20, 2016·British Journal of Haematology·Amanda M BrandowJulie A Panepinto
Apr 14, 2009·Journal of Pediatric Surgery·Rahul K Shah, Lina Lander
Oct 21, 2016·Pediatric Blood & Cancer·Jennifer HorstEvan D Kharasch
Mar 26, 2008·The Journal of Craniofacial Surgery·Raj M VyasJames P Bradley
Oct 9, 2015·Journal of Transcultural Nursing : Official Journal of the Transcultural Nursing Society·Nancy LaboreBiree Andemariam
Feb 22, 2017·Pain·Amanda M BrandowCheryl L Stucky
Nov 25, 2014·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Marian B Fosdal
Mar 13, 2012·Journal of Child Neurology·Shannon M Standridge, Paul S Horn
Aug 13, 2017·Pediatric Blood & Cancer·Laura M Bou-MarounGregory A Yanik
Oct 27, 2018·Pediatric Blood & Cancer·Anurag K AgrawalAnne Marsh
Apr 18, 2009·Health and Quality of Life Outcomes·Julie A PanepintoNicholas M Pajewski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.