PMID: 52587Sep 20, 1975Paper

Variation in human acrocentric chromosomes with acridine orange reverse banding

Humangenetik
R S Verma, H A Lubs

Abstract

Twenty-five normal subjects were studied by acridine orange reverse (RFA) banding in order to obtain a preliminary estimate of the type and frequency of variations in color and length. Color variations were classified into 1 of 6 colors and size variations into 1 of 5 levels. The same cells were also studied by Q banding. Acridine orange reverse banding was found to be more useful than Q banding for characterizing variations in chromosomes 14, 15, 21 and 22. In addition, it was found that there was no consistent relationship between pale or bright Q banding and the various colors observed with RFA banding. For the optimal characterization of a chromosomal variation, multiple banding technics, including RFA banding, are necessary.

References

Jan 1, 1975·Cytogenetics and Cell Genetics·W H McKenzie, H A Lubs
Jan 1, 1973·Pediatric Research·S MerrickH A Lubs
Jan 1, 1974·Chromosoma·K W JonesG Corneo
Oct 1, 1972·Computers in Biology and Medicine·R S LedleyF H Ruddle

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Citations

Jan 19, 1978·Human Genetics·Y NakagomeM Higurashi
Jan 1, 1984·Molecular & General Genetics : MGG·R S Verma, K A Babu
Mar 1, 1986·Molecular & General Genetics : MGG·R S VermaH Dosik
Mar 15, 1985·Cancer Genetics and Cytogenetics·K O Goh
Apr 1, 1990·Cancer Genetics and Cytogenetics·G Juliusson, G Gahrton
Mar 1, 1979·Canadian Journal of Genetics and Cytology. Journal Canadien De Génétique Et De Cytologie·R S Verma, H Dosik
Mar 1, 1978·Jinrui idengaku zasshi. The Japanese journal of human genetics·R S Verma, H Dosik
Jul 1, 1988·American Journal of Medical Genetics·C JonesI M Rosenthal
Jan 1, 1980·Human Genetics·E ThermanM Ulber
Mar 1, 1977·Clinical Genetics·R S VermaH A Lubs

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