PMID: 9423575Jan 10, 1998Paper

Variation in incidences of tuberculosis in subgroups of South African gold miners

Occupational and Environmental Medicine
I Kleinschmidt, Gavin J Churchyard

Abstract

To determine risk factors and to identify groups at high risk of tuberculosis (TB) among South African gold miners. A retrospective cohort analysis was carried out with hospital and personnel databases on a random sample of the workforce of Freegold Mines, served by Ernest Oppenheimer Hospital, Welkom, South Africa. The outcome measure of interest was a reported first episode of TB while employed at Freegold. A person-years analysis was carried out to estimate incidence ratios between different categories of age group, period, cumulative service, mining occupation, and silicosis status. A separate analysis was carried out on a subgroup of men (non-random) whose HIV status was known. The main finding of the study was that TB was more strongly associated with age than expected with a rate ratio of reported incidence of 21 for the oldest age group compared with the youngest, after adjustment for period, cumulative service, occupation, and silicosis status. There was also a significant association between TB and occupations such as drilling with a rate ratio of 2.3 compared with low dust surface and maintenance workers, after adjustment for age, period, cumulative service, and silicosis. Analysis of the HIV tested subgroup showed t...Continue Reading

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Citations

May 14, 2004·The New England Journal of Medicine·C Robert Horsburgh
Feb 25, 2006·Occupational and Environmental Medicine·J M teWaternaudeJ E Myers
Nov 17, 1998·Occupational and Environmental Medicine·E Hnizdo, J Murray
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·E L CorbettK M De Cock
May 1, 2007·Indian Journal of Occupational and Environmental Medicine·Rajnarayan R TiwariHabibullah N Saiyed
Jul 9, 2010·Scandinavian Journal of Infectious Diseases·Chih-Cheng LaiPo-Ren Hsueh
Apr 11, 2008·Respirology : Official Journal of the Asian Pacific Society of Respirology·Hye-Ryoun KimJae-Joon Yim
Jan 7, 1999·International Journal of Occupational and Environmental Health·B Williams, C Campbell
Jan 9, 2007·New Solutions : a Journal of Environmental and Occupational Health Policy : NS·R M Lynch, I Mbaye
Sep 22, 2018·American Journal of Industrial Medicine·Rodney EhrlichDavid Rees
Jun 28, 2005·American Journal of Respiratory and Critical Care Medicine·Kevin M De Cock, Barbara Marston
May 8, 1998·Nature·R Race, B Chesebro
Jun 1, 2019·American Journal of Respiratory and Critical Care Medicine·Paul D BlancCarrie A Redlich
Sep 10, 2021·Public Health Reports·Nicholas K ReulMargaret A Leland

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