Variation in Prosthetic Joint Infection and treatment strategies during 4.5 years of follow-up after primary joint arthroplasty using administrative data of 41397 patients across Australian, European and United States hospitals

BMC Musculoskeletal Disorders
Perla J Marang-van de MheenAndrew Gordon

Abstract

To identify best practices and quality improvement initiatives, we aimed to assess whether the incidence of Periprosthetic Joint Infection (PJI) and treatment strategies differed across patients treated in Australian, European and United States (US) hospitals. Routinely collected administrative data for 41397 patients undergoing a primary total hip or knee arthroplasty between July 2007-December 2010 across 22 hospitals were included. Patients were followed for 2 years looking for PJI occurrence, defined as early (within 4 weeks) and late PJI, and surgical treatment during 2.5 years after PJI diagnosis. Logistic and Poisson regression models were used to test for differences in PJI occurrence and treatment strategies across the three geographical regions, adjusted for age, sex, joint and Elixhauser comorbidity groups. PJI occurrence varied from 1.4% in European to 1.7% in Australian patients, which were significantly higher than US patients after adjustment for patient characteristics (OR 1.24 [1.01-1.52] and 1.40 [1.03-1.91] respectively). Early PJIs varied between 0.3% in European to 0.6% in Australian patients, but adjusted rates were similar. Revision following PJI was significantly lower in Australian than in US patients (...Continue Reading

References

Dec 2, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·K B KirklandD J Sexton
Sep 24, 2005·Health Services Research·Kimberly J O'MalleyCarol M Ashton
Apr 19, 2008·Clinical Orthopaedics and Related Research·Luis PulidoJavad Parvizi
Mar 19, 2009·Health Information Management : Journal of the Health Information Management Association of Australia·Ping ChengLindsay Paul
Apr 11, 2009·Clinical Orthopaedics and Related Research·Steven M KurtzKevin J Bozic
Mar 16, 2011·International Orthopaedics·Steven M KurtzChristoph Röder
Apr 25, 2012·The Journal of Bone and Joint Surgery. British Volume·I S VanheganF S Haddad
Oct 23, 2012·Acta Orthopaedica·Håvard DaleLars B Engesæter
Nov 13, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Geoffrey TsarasElie F Berbari
Apr 18, 2014·The Journal of Bone and Joint Surgery. American Volume·Steven M KurtzKevin J Bozic
Apr 18, 2014·The Journal of Bone and Joint Surgery. American Volume·Kevin J BozicElizabeth E Drye
Mar 18, 2015·Acta Orthopaedica·Johannes Cornelis SchramaBjørg-Tilde Fevang
Mar 19, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Leon J WorthMichael J Richards
Jun 26, 2015·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Jeppe LangeKjeld Søballe
Sep 4, 2015·The Journal of Bone and Joint Surgery. American Volume·Hilal Maradit KremersDaniel J Berry

❮ Previous
Next ❯

Citations

Nov 24, 2018·BMJ Quality & Safety·Christopher Kandel, Nick Daneman
May 18, 2019·BJOG : an International Journal of Obstetrics and Gynaecology·H S LipkindA A Merriam
Oct 1, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Christopher E KandelAllison McGeer
Jul 11, 2018·Current Reviews in Musculoskeletal Medicine·Fiachra E RowanFares S Haddad
Dec 23, 2020·The Journal of Infection·Adrien LemaignenUNKNOWN Scientific Committee for Complex Bone and Joint Infections Reference Centers (CRIOAc), on behalf of the CRIOAc network
Dec 9, 2020·Journal of Infection and Public Health·Enrico Maria Zardi, Francesco Franceschi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved