PMID: 2499560Feb 1, 1989Paper

Variation in the amount and activity of esterase 6 in a natural population of Drosophila melanogaster

Heredity
A Y Game, J G Oakeshott

Abstract

Forty-two homozygous lines each isoallelic for the Esterase 6 (Est-6) locus were extracted from a natural population of Drosophila melanogaster. Homogenates of 4-5 day old virgin adults of each sex from several replicate cultures of each line were assayed for EST6 activity. Depending on the line, males had from three to nine times more EST6 activity than females. Both sexes showed highly significant differences in EST6 activity among lines, with 3.2 and 2.7 fold differences between highest and lowest lines for males and females respectively. However, the variation in EST6 activity among lines was only weakly correlated across the two sexes. Female EST6 activity did not differ significantly across the six electrophoretic variants of EST6 found among the 42 lines. On the hand, a significant proportion of the variation among lines in male EST6 activity could be explained by differences among the six electromorphs. However, most of these differences were due to the relatively high activities of males from two relatively rare electromorphs and there were no significant differences in male activity among the four more common EST6 electromorphs. Radial immunodiffusion assays with polyclonal anti-EST6 antibody established that differen...Continue Reading

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Citations

Mar 1, 1995·Trends in Ecology & Evolution·J H OakeshottM J Healy
Jan 1, 1993·Genetica·J G OakeshottR J Russell
Dec 22, 2011·Molecular Systems Biology·Anthony J GreenbergAndrew G Clark
Dec 1, 1998·Evolution; International Journal of Organic Evolution·Lawrence G Harshman, Jeana L Schmid

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