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Variation in transcription factor binding among humans

Science

Mar 20, 2010

Maya KasowskiMichael Snyder

Abstract

Differences in gene expression may play a major role in speciation and phenotypic diversity. We examined genome-wide differences in transcription factor (TF) binding in several humans and a single chimpanzee by using chromatin immunoprecipitation followed by sequencing. The binding site...read more

Mentioned in this Paper

RNA Polymerase II
Immune Response
DNA, Junk
DNA Copy Number Changes
Transcription Initiation Site
Chromatin Immunoprecipitation
Plasma Protein Binding Capacity
Gene Expression
Pan troglodytes
Sequencing
1
1
805
1
Paper Details
References
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  • Citations273
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  • References16
  • Citations273
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Related Papers

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Variation in transcription factor binding among humans

Science

Mar 20, 2010

Maya KasowskiMichael Snyder

PMID: 20299548

DOI: 10.1126/science.1183621

Abstract

Differences in gene expression may play a major role in speciation and phenotypic diversity. We examined genome-wide differences in transcription factor (TF) binding in several humans and a single chimpanzee by using chromatin immunoprecipitation followed by sequencing. The binding site...read more

Mentioned in this Paper

RNA Polymerase II
Immune Response
DNA, Junk
DNA Copy Number Changes
Transcription Initiation Site
Chromatin Immunoprecipitation
Plasma Protein Binding Capacity
Gene Expression
Pan troglodytes
Sequencing
1
1
805
1

Feeds With Similar Papers

Eukaryotic RNA Polymerase II (Keystone)

RNA polymerase II (RNAP II) is a 550 kDa multiprotein complex composed of 12 subunits. Here is the latest research on RNAP II and its role it regulating transcription and transcription-coupled recombination repair.

Science eTOC

Science Magazine is a peer-reviewed academic journal of the American Association for the Advancement of Science. Find the latest research from Science here.

Paper Details
References
  • References16
  • Citations273
12
  • References16
  • Citations273
12345...

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