Variation of bone layer thicknesses and trabecular volume fraction in the adult male human calvarium

Bone
Sourabh BoruahJeff R Crandall

Abstract

The human calvarium is a sandwich structure with two dense layers of cortical bone separated by porous cancellous bone. The variation of the three dimensional geometry, including the layer thicknesses and the volume fraction of the cancellous layer across the population, is unavailable in the current literature. This information is of particular importance to mathematical models of the human head used to simulate mechanical response. Although the target geometry for these models is the median geometry of the population, the best attempt so far has been the scaling of a unique geometry based on a few median anthropometric measurements of the head. However, this method does not represent the median geometry. This paper reports the average three dimensional geometry of the calvarium from X-ray computed tomography (CT) imaging and layer thickness and trabecular volume fraction from micro CT (μCT) imaging of ten adult male post-mortem human surrogates (PMHS). Skull bone samples have been obtained and μCT imaging was done at a resolution of 30 μm. Monte Carlo simulation was done to estimate the variance in these measurements due to the uncertainty in image segmentation. The layer thickness data has been averaged over areas of 5mm(2)....Continue Reading

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Citations

Oct 17, 2016·Journal of the Mechanical Behavior of Biomedical Materials·Sourabh BoruahRobert S Salzar
May 29, 2020·American Journal of Physical Anthropology·Gizéh Rangel-de LázaroEmiliano Bruner
May 6, 2017·Medical & Biological Engineering & Computing·V Phanindra BoguAsit Kumar Khanra
Dec 12, 2018·Journal of the Mechanical Behavior of Biomedical Materials·Stephen L AlexanderTusit Weerasooriya
Mar 27, 2021·Bone·Kevin AdantyChristopher R Dennison

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