Variation of bone layer thicknesses and trabecular volume fraction in the adult male human calvarium

Sourabh BoruahJeff R Crandall


The human calvarium is a sandwich structure with two dense layers of cortical bone separated by porous cancellous bone. The variation of the three dimensional geometry, including the layer thicknesses and the volume fraction of the cancellous layer across the population, is unavailable in the current literature. This information is of particular importance to mathematical models of the human head used to simulate mechanical response. Although the target geometry for these models is the median geometry of the population, the best attempt so far has been the scaling of a unique geometry based on a few median anthropometric measurements of the head. However, this method does not represent the median geometry. This paper reports the average three dimensional geometry of the calvarium from X-ray computed tomography (CT) imaging and layer thickness and trabecular volume fraction from micro CT (μCT) imaging of ten adult male post-mortem human surrogates (PMHS). Skull bone samples have been obtained and μCT imaging was done at a resolution of 30 μm. Monte Carlo simulation was done to estimate the variance in these measurements due to the uncertainty in image segmentation. The layer thickness data has been averaged over areas of 5mm(2)....Continue Reading


Jan 1, 1977·American Journal of Physical Anthropology·O J Oyen, A Walker
Jul 1, 1975·American Journal of Physical Anthropology·A AdeloyeF N Silverman
May 1, 1985·Plastic and Reconstructive Surgery·J Pensler, J G McCarthy
Oct 1, 1970·Journal of Biomechanics·J H McElhaneyN M Alem
Jan 1, 1969·American Journal of Physical Anthropology·M J Baer, J E Harris
Jun 1, 1995·Acta Odontologica Scandinavica·J Huggare, Rönning
May 1, 1997·The Journal of Craniofacial Surgery·K HwangS H Baik
May 1, 1997·The Journal of Craniofacial Surgery·M M ElahiJ Sampalis
May 30, 1998·The Anatomical Record·V M Spitzer, D G Whitlock
Sep 15, 1998·IEEE Transactions on Medical Imaging·D L CollinsA C Evans
Jun 22, 1999·Annals of Biomedical Engineering·R WillingerB Diaw
Mar 7, 2001·Forensic Science International : Synergy·N Lynnerup
Apr 21, 2001·The Journal of Craniofacial Surgery·K HwangS I Lee
Jul 12, 2001·Annual Review of Biomedical Engineering·T M KeavenyO C Yeh
Nov 10, 2001·Annual Review of Biomedical Engineering·D L PhamJ L Prince
Sep 5, 2002·The Anatomical Record·Jill Peterson, Paul C Dechow
Jun 13, 2003·Nature·Tim D WhiteF Clark Howell
Mar 22, 2005·Clinical Oral Implants Research·Ingrid Le Lorc'h-BukietPhilippe Lesclous
May 3, 2006·Plastic and Reconstructive Surgery·Andrea Moreira-GonzalezJames E Zins
Jul 30, 2008·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Saxby BrownClive Baldock
Nov 11, 2008·Forensic Science International : Synergy·Hatice Gul HatipogluEnis Yuksel
Jan 29, 2009·IEEE Transactions on Bio-medical Engineering·Steffen H TretbarPhilipp A Federspil
May 20, 2009·Journal of Biomechanical Engineering·Paul A Taylor, Corey C Ford
Oct 7, 2009·Annals of Biomedical Engineering·M S ChafiM Ziejewski
Nov 21, 2009·American Journal of Physical Anthropology·John H Relethford
Feb 2, 2010·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Daniel Torres-LagaresPhilippe Lesclous
Nov 26, 2010·Proceedings of the National Academy of Sciences of the United States of America·Michelle K NyeinRaul A Radovitzky
May 10, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Atson Carlos de Souza FernandesMárcio de Moraes
Jul 26, 2011·Annals of Biomedical Engineering·F S GayzikJoel D Stitzel
Dec 27, 2011·Forensic Science International : Synergy·Vedat SabancıoğullarıMehmet Cimen
Feb 3, 2012·Annals of Biomedical Engineering·Matthew B PanzerCameron R Bass
May 22, 2013·Journal of the Mechanical Behavior of Biomedical Materials·Z AsgharpourS Peldschus
Sep 26, 2013·Journal of Biomechanical Engineering·Haojie MaoKing H Yang
Dec 3, 2013·International Journal for Numerical Methods in Biomedical Engineering·Dilaver SinghTyler N Haladuick
Jan 30, 2014·Traffic Injury Prevention·Calvin LeeCameron R Bass
Dec 3, 2014·Journal of Anatomy·Elizabeth M LillieJoel D Stitzel
Dec 30, 2014·American Journal of Human Biology : the Official Journal of the Human Biology Council·Marisol AnzelmoMarina L Sardi


Oct 17, 2016·Journal of the Mechanical Behavior of Biomedical Materials·Sourabh BoruahRobert S Salzar
May 29, 2020·American Journal of Physical Anthropology·Gizéh Rangel-de LázaroEmiliano Bruner
May 6, 2017·Medical & Biological Engineering & Computing·V Phanindra BoguAsit Kumar Khanra
Dec 12, 2018·Journal of the Mechanical Behavior of Biomedical Materials·Stephen L AlexanderTusit Weerasooriya
Mar 27, 2021·Bone·Kevin AdantyChristopher R Dennison

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