PMID: 2498015Apr 1, 1989Paper

Variation of total pepsin activity in sera with age and under different stimulations of gastric acid secretion

Clinical Biochemistry
S MassarratE R Schwarz

Abstract

The total pepsin activity in sera was measured in 660 outpatients endoscopically proven to be free of gastroduodenal lesions. A small but significant increase of total pepsin activity with age in females older than 50 years was observed. Total serum pepsin activity increased after stimulation of gastric acid secretion. This increase was small after a meal and vagal stimulation by sham feeding, but higher after maximal stimulation with Pentagastrin. Its amount, which is in general rather small and probably not relevant for clinical evaluation of gastric acid secretion, depends on the proportion of cases with high gastric secretory capacity. This might clarify the discrepancy in the results obtained by previous authors.

References

Apr 14, 1976·Biochimica Et Biophysica Acta·M ZöllerW Rapp
Sep 28, 1976·Biochimica Et Biophysica Acta·S Matzku, W Rapp
Jan 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·A J Lombarts, H J Peters
Aug 1, 1966·Gut·V Ilic, G H Spray
Feb 1, 1983·The Tohoku Journal of Experimental Medicine·C NakanomeY Goto
Dec 9, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·M IchinoseK Takahashi
Aug 18, 1955·The New England Journal of Medicine·H M SPIROC M JONES
Oct 1, 1964·The Journal of Clinical Investigation·I KUSHNERP BURTIN

❮ Previous
Next ❯

Citations

Jan 6, 2006·The Cancer Journal·Rishi SawhneyArash Naeim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.