PMID: 2479245May 1, 1989Paper

Variations in antigen-specific histamine release related with immunotherapeutic treatment.

Allergologia et immunopathologia
J G CastilloC G de la Cuesta

Abstract

The present study analyzes the variations in the percentage of histamine release of 34 allergic patients receiving immunotherapy; the determinations were realized at two different periods of their immunotherapeutic treatment, that is, at an average of 18 months (mite allergy group) and 12 months (grass allergy group) after the first determination. We found that the percentage of histamine release decreased significantly in the second determination in relation to the first, and that this decrease was more intense when more time elapsed between both determinations.

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.